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Diss Factsheets

Physical & Chemical properties

Melting point / freezing point

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Administrative data

Link to relevant study record(s)

Reference
Endpoint:
melting point/freezing point
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
other: According to international guideline(s), GLP-compliant, performed in recognized contract research organization, no restrictions, fully adequate for assessment.
Qualifier:
according to guideline
Guideline:
OECD Guideline 102 (Melting point / Melting Range)
Deviations:
no
Qualifier:
according to guideline
Guideline:
EU Method A.1 (Melting / Freezing Temperature)
Deviations:
no
GLP compliance:
yes (incl. QA statement)
Type of method:
capillary method
Melting / freezing pt.:
28 - 31 °C
Melting / freezing pt.:
301 - 304 K

Pre-Test:

Room Temperature: liquid and colourless

5 °C and -20 °C:     solid

 

Main test (begin and end of the melting process):

First determination: : 28.2 and 31.0 °C (301.4 and 304.2 K)

Second determination: 28.8 and 30.5 °C (301.4 and 303.7 K)

 

The original test item is a liquid which can be tempered to even 20 °C without solidification (e.g. endpoint study record 4.4 Density). After storage at 5 °C or lower solidification occurred and the test item stayed in solid state at room temperature. This effect indicates that the original test item is a supercooled liquid.

 

The difference between the duplicate determinations was in the range of the estimated accuracy of the method (± 0.5 K).

The difference between the temperature at the beginning and at the final stage of melting was not within the limits of the accuracy of the method. Thus, the two temperatures are reported (melting range).

Description of key information

melting point 28- 31 °C (OECD 102, EU A.1)

Key value for chemical safety assessment

Melting / freezing point at 101 325 Pa:
30 °C

Additional information