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EC number: 242-555-3 | CAS number: 18755-43-6
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Endpoint summary
Administrative data
Description of key information
Additional information
Based on the presented results dimethyl propylphosphonate has to be scored as not harmful towards aquatic organisms. Data on aquatic effects of dimethyl propylphosphonate are available on three trophic levels (fish, daphnia and algae) for acute toxicity.
In order to test the acute toxicity to fish, Brachydanio rerio was exposed to the test solution of one nominal concentration of dimethyl propylphosphonate (100 mg/L) and blank control solution for a period of 96 h under static conditions. The measured concentrations confirmed that deviation from the nominal concentrations were less than 20 % (measured concentrations were in the range of 94.0 - 104.9 % of nominal concentrations). No toxic effect and abnormal behavior were observed. This toxicity study meets the requirements of the guideline for the acute fish studies.
A LC0 ≥ 99.1 mg/L (arithmetic mean of the analytically determined test concentrations) was determined.
Concerning the toxicity towards aquatic invertebrates, an acute toxicity test to Daphnia magna was performed according to OECD Guideline 202 (Daphnia sp. Acute Immobilisation Test). No toxic effect and abnormal behavior were observed during 48 h of exposure. As analytical monitoring was performed showing stability of dimethyl propylphosphonate, the results of EC50 > 90 mg/L and EC0 >= 90 mg/L relate to measured initial concentrations.
In a toxicity test towards algae, the fresh water alga Desmodesmus subspicatus was exposed to dimethyl propylphosphonate for 72 h. The experiment was conducted according to OECD Guideline 201 (Alga, Growth Inhibition Test). An EC50 > 88.4 mg/L and a NOEC >= 88.4 mg/L, based on measured initial concentrations was obtained in this test. Analytical monitoring was carried out and stability of dimethyl propylphosphonate was confirmed during the duration of exposure.
In order to test the toxicity of dimethyl propylphosphonate to microorganisms, activated sludge from a laboratory sewage treatment plant was exposed to the test solution of three nominal concentrations of dimethyl propylphosphonate (100, 1000 and 10000 mg/L), blank control solution and solution with positive reference substance for a period of 3 h. Dissolved oxygen was recorded and respiration rates were calculated. No physicochemical oxygen consumption was observed at the highest concentration of dimethyl propylphosphonate. No respiration inhibition was observed at 100 and 1000 mg/L; and only 9.5 % inhibition at 10000 mg/L. This toxicity study meets the requirements of the guideline for the acute microorganism studies.
An EC50 >10000 mg/L was determined in this test.
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