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EC number: 214-189-4 | CAS number: 1112-39-6
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Other distribution data
Administrative data
- Endpoint:
- other distribution data
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- study well documented, meets generally accepted scientific principles, acceptable for assessment
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 011
- Report date:
- 2011
Materials and methods
Test guideline
- Qualifier:
- no guideline followed
- Principles of method if other than guideline:
- - Principle of test:
The objective was to derermine the distribution of Dimethylsilanediol (DMSD) in air, water, octanol systems and the dependence of these distributions from temperature. Therefore a three phase system (air, octanol, water) was used. The Kaw, Kow and Koa were determined.
- Short description of test conditions: A 100 mL borosilicate glass syringe was used in which a three phase system of air, octanol and water was established for the experiments. The experiment was conducted in an incubator in which the temperature was controlled.
- Parameters analysed / observed: The distribution/concentration of the substance between the three phases was measured via reversed phase HPLC/RAM, Normal phase HPLC/RAM and LSC Analysis. - GLP compliance:
- no
- Type of study:
- other: Distribution of DMSD in a three phase system octanol - air - water system
- Media:
- other: air - octanol - water
Test material
- Reference substance name:
- Dimethylsilanediol
- EC Number:
- 213-915-7
- EC Name:
- Dimethylsilanediol
- Cas Number:
- 1066-42-8
- Molecular formula:
- C2H8O2Si
- IUPAC Name:
- Dimethylsilanediol
1
Results and discussion
Any other information on results incl. tables
- The reversed phase HPLC chromatogram of DMSD-containing water showed small fraction (2 -5%) of dimer diol in the three phase equilibrium.
- Normal phase HPLC chromatograms of the 1-octanol from the three-phase equilibrium clearly indicated the existence of dimer diol, trimer diol and up to 6 compounds with shorter retention times than DMSD, especially for 35 °C.
- In previeous study equilibrium was found to be reached within 2 h if the equilibration started from DMSD containing water at 20 °C (Xu and Kropscott, 2011). The shortest time for all experiments was close to 20 h but no obvious deviation from their corresponding average values was observed.
- Overall, the values of log Kaw, log Koa and log Kow were relatively constant over time at each temperature.
- The measured partition coefficients were, obtained from a three-phase equilibrium state.
When the average values of three partition coefficients at four temperatures were plotted against the reciprocal of the equilibrium temperature, three linear correlations were obtained as follows:
log Kaw= -19.70 + 3739.5/T R2= 0.974 (n = 4)
log Koa= 21.34 - 4328.9/T R2= 0.980 (n = 4)
log Kow= 1.67 - 604.2/T R2= 0.988 (n = 4)
Based on these equations the partition coefficients for 25 °C were:
- log Kaw = -7.16,
- log Koa = 6.82,
- log Kow = -0.36
Measured values of partition coefficients in the current study are consistent with the log Kaw value measured at 35 °C using a syringe system containing water/air phases only (Xu and Kropscott, 2011).
Reference: Xu, S. and Kropscott, B. 2011. A Method for Determining Environmental Partition Coefficients of Dimethylsilanediol under Various Conditions.
Applicant's summary and conclusion
- Conclusions:
- The study determined the distribution of Dimethylsilanediol (DMSD) in a three phase system (air, water, octanol). The partition coefficients for 25 °C were log Kaw = -7.16, log Koa = 6.82 and log Kow = -0.36 in the three phase system.
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