Registration Dossier
Registration Dossier
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EC number: 617-448-3 | CAS number: 83196-56-9
Acute Toxicity: oral
Administrative data
- Endpoint:
- acute toxicity: oral
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 3 (not reliable)
- Rationale for reliability incl. deficiencies:
- other: A non GLP study without details
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 1 992
- Report date:
- 1992
Materials and methods
Test guideline
- Qualifier:
- no guideline available
- Principles of method if other than guideline:
- No further details
- GLP compliance:
- no
Test material
- Reference substance name:
- Androsta-4,9(11)-diene-17-carbonitrile, 17-hydroxy-3-oxo-, (17α)-
- IUPAC Name:
- Androsta-4,9(11)-diene-17-carbonitrile, 17-hydroxy-3-oxo-, (17α)-
- Reference substance name:
- Androsta-4,9(11)-diene-17-carbonitrile, 17-hydroxy-3-oxo-, (17a)-
- EC Number:
- 617-448-3
- Cas Number:
- 83196-56-9
- Molecular formula:
- C20H25NO2
- IUPAC Name:
- Androsta-4,9(11)-diene-17-carbonitrile, 17-hydroxy-3-oxo-, (17a)-
Constituent 1
Constituent 2
Test animals
- Species:
- rat
- Strain:
- not specified
- Sex:
- not specified
Administration / exposure
- Route of administration:
- oral: unspecified
- Vehicle:
- maize oil
- Doses:
- 25, 200, 2000 mg/kg (Volume 10 ml/kg)
- Control animals:
- not specified
Results and discussion
Effect levels
- Sex:
- not specified
- Dose descriptor:
- LD50
- Effect level:
- > 2 000 mg/kg bw
- Based on:
- test mat.
- Mortality:
- No mortality at doses 25, 200, 2000 mg/kg
Applicant's summary and conclusion
- Interpretation of results:
- not classified
- Remarks:
- Migrated information Criteria used for interpretation of results: EU
- Conclusions:
- The oral LD50 in rats after a single dose of decyandrostenone, is > 2000 mg/kg .
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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