Registration Dossier
Registration Dossier
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EC number: 405-400-2 | CAS number: 54253-62-2 KUPFER-II-METHANSULFONAT; KUPFERMETHANSULFONAT
Skin irritation / corrosion
Administrative data
- Endpoint:
- skin irritation: in vivo
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: study conducted by GLP accredited lab according to recognised guideline method. Data provided by ECHA from migrated NONS file. Litle detail available.
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 1 990
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- other: Annex V
- GLP compliance:
- yes
Test material
- Reference substance name:
- Copper(II) methanesulfonate
- EC Number:
- 405-400-2
- EC Name:
- Copper(II) methanesulfonate
- Cas Number:
- 54253-62-2
- Molecular formula:
- C2H6CuO6S2
- IUPAC Name:
- copper(2+) dimethanesulfonate
- Test material form:
- not specified
Constituent 1
Test animals
- Species:
- rabbit
- Strain:
- New Zealand White
Test system
- Type of coverage:
- semiocclusive
- Vehicle:
- water
- Amount / concentration applied:
- 0.5g
- Duration of treatment / exposure:
- 4h
- Observation period:
- 7 days
- Number of animals:
- 3
Results and discussion
In vivo
Resultsopen allclose all
- Irritation parameter:
- erythema score
- Basis:
- other: max value
- Time point:
- other: 72h
- Max. score:
- 2
- Reversibility:
- fully reversible within: 7 days
- Remarks on result:
- other: no additional information provided
- Irritation parameter:
- edema score
- Time point:
- other: 48h
- Max. score:
- 2
- Reversibility:
- fully reversible within: 7 days
- Remarks on result:
- other: no additional information provided
Any other information on results incl. tables
Erythema/eschar persisted for 72h and had a maximum score of 2.
Oedema persisted for 48h and had a maximum score of 2.
All changes were reversible within 7 days.
Applicant's summary and conclusion
- Interpretation of results:
- not classified
- Remarks:
- Migrated information Criteria used for interpretation of results: EU
- Conclusions:
- the substance is not a skin irritant
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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