Registration Dossier
Registration Dossier
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EC number: 700-483-4 | CAS number: -
Endpoint summary
Administrative data
Description of key information
Additional information
Since RAV 7NG contains as main ingredient 'diallyl 2,2'oxydiethyl dicarbonate' and experimental data are lacking for RAV 7NG, the experimental data from 'diallyl 2,2'oxydiethyl dicarbonate' were used in a read-across approach.
Justification for read-across from supporting substance RAV 7AT (diallyl 2,2'-oxydiethyl dicarbonate; CAS 142-22-3; EC 205-528-7): about 70 % of RAV 7NG (EC 700-483-4) consists of components that can be found in the commercial ADC grades known as RAV 7AT, Nouryset 200 and CR39. Merely from comparing the similar production processes of these two substances it is apparent that RAV 7AT and RAV 7NG are closely related to each other. Finally, the physical-chemical, toxicological and ecotoxicological properties of RAV 7NG and RAV 7AT are almost equal and as a result, read across is justified.
'Diallyl 2,2'-oxydiethyl dicarbonate' is not expected to be accumulative in organisms due to the substance specific logPow of 1.543. Therefore no experiments regarding aquatic or terrestrial bioaccumulation potential have to be conducted according to REACH regulation. For completeness, a QSAR calculation was performed with the help of the US-EPA computer tool EPIWIN (BCFBAFv3.00), resulting in an aquatic bioconcentration factor (BCF) of 4.843 L/kg wet weight (Chemservice S.A., 2010). This low BCF value confirms the low bioaccumulation potential of the test substance. The terrestrial bioaccumulation potential is no mandatory requirement under REACH for 'diallyl 2,2'-oxydiethyl dicarbonate'.Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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