Registration Dossier
Registration Dossier
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EC number: 202-437-4 | CAS number: 95-64-7
Short-term toxicity to aquatic invertebrates
Administrative data
- Endpoint:
- short-term toxicity to aquatic invertebrates
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 4 (not assignable)
Data source
Referenceopen allclose all
- Reference Type:
- review article or handbook
- Title:
- Results of the Harmful Effects of Water Pollutants to Daphnia magna in the 21 Day Reproduction Test
- Author:
- Kuhn, R., M. Pattard, K.D. Pernak, and A. Winter
- Year:
- 1 989
- Bibliographic source:
- ECOTOX (ECOTOXicology database); Water Res.23(4): 501-510
- Reference Type:
- other: QSAR toolbox
- Title:
- No information
- Year:
- 2 011
- Bibliographic source:
- OECD QSAR toolbox version 2.2, 2011; Phys-chem EPISUITE; PERRIN,DD (1972)
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- other: Modelling database
- Principles of method if other than guideline:
- QSAR estimation database
- GLP compliance:
- no
Test material
- Reference substance name:
- 3,4-xylidine
- EC Number:
- 202-437-4
- EC Name:
- 3,4-xylidine
- Cas Number:
- 95-64-7
- Molecular formula:
- C8H11N
- IUPAC Name:
- 3,4-dimethylaniline
Constituent 1
Test organisms
- Test organisms (species):
- Daphnia magna
Study design
- Test type:
- static
- Water media type:
- freshwater
- Total exposure duration:
- 24 h
Test conditions
- Test temperature:
- Water Temperature 25 Celsius
- pH:
- Water pH ≥7
- Dissolved oxygen:
- Water Dissolved Oxygen ≥58 percent
Results and discussion
Effect concentrationsopen allclose all
- Duration:
- 24 h
- Dose descriptor:
- EC50
- Effect conc.:
- 2.9 mg/L
- Nominal / measured:
- meas. (not specified)
- Conc. based on:
- test mat.
- Basis for effect:
- other: Intoxication
- Duration:
- 24 h
- Dose descriptor:
- EC0
- Effect conc.:
- 0.2 mg/L
- Nominal / measured:
- meas. (not specified)
- Conc. based on:
- test mat.
- Basis for effect:
- behaviour
Applicant's summary and conclusion
- Executive summary:
3,4 xylidine is toxic to the aquatic environment.
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