Registration Dossier
Registration Dossier
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EC number: 216-074-4 | CAS number: 1490-04-6
Carcinogenicity
Administrative data
Description of key information
A bioassay of dl-menthol for possible carcinogenicity was conducted by administrating the test chemical in feed to Fisher 344 rats and B6C3F1 mice.
Key value for chemical safety assessment
Justification for classification or non-classification
From the available studies a claassification is not justified
Additional information
In male rats, no tumors occured at incidences which were considered to be related to the administration of dl-menthol.
In female rats, no tumors occured at higher incidences in the dosed groups than in the control groups.
In mice of either sex, no tumors occured in dosed groups at incidences that were significantly different from those for corresponding control groups
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