Registration Dossier
Registration Dossier
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EC number: 221-453-2 | CAS number: 3101-60-8
Endpoint summary
Administrative data
Description of key information
The test substance, p-tert-butylphenyl-1-(2,3)-epoxypropyl ether was accessed for both acute oral and dermal toxicity in the rat by O.E.C.D. test guideline studies.
Key value for chemical safety assessment
Acute toxicity: via oral route
Endpoint conclusion
- Endpoint conclusion:
- no adverse effect observed
- Dose descriptor:
- LD50
- Quality of whole database:
- Not applicable
Acute toxicity: via inhalation route
Endpoint conclusion
- Endpoint conclusion:
- no study available
Acute toxicity: via dermal route
Endpoint conclusion
- Endpoint conclusion:
- no adverse effect observed
- Dose descriptor:
- LD50
- Quality of whole database:
- Not applicable
Additional information
The acute oral and dermal LD50 values for the test substance to the rat were both > 2000 mg/Kg of body weight. No adverse findings were observed in either study.
Justification for selection of acute toxicity – oral endpoint
As per O.E.C.D. test guideline requirement with GLP compliance.
Justification for selection of acute toxicity – dermal endpoint
As per O.E.C.D. test guideline no. 402 with GLP compliance.
Justification for classification or non-classification
With acute oral and dermal LD50 values of > 2000 mg/Kg of body weight no Classification and Labeling for acute toxic effects is not required.
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