Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Description of key information

For the oral toxicity  an LD50 of 735 mg/kg bw is found,
For dermal toxicity no mortality occured at the limit dose and the LD50 is by default 2000 mg/kg bw.
No inhalative toxicological study is available.

Key value for chemical safety assessment

Acute toxicity: via oral route

Endpoint conclusion
Endpoint conclusion:
adverse effect observed
Dose descriptor:
LD50
Value:
735 mg/kg bw
Quality of whole database:
There are two studies available, the key study is rated Klimisch 1, the supporting study Klimisch 2.

Acute toxicity: via inhalation route

Endpoint conclusion
Endpoint conclusion:
no study available

Acute toxicity: via dermal route

Endpoint conclusion
Endpoint conclusion:
no adverse effect observed
Dose descriptor:
LD50
Value:
2 000 mg/kg bw
Quality of whole database:
The study is performed similar to OECD Guideline and rated Klimisch 2

Additional information

Justification for selection of acute toxicity – oral endpoint
This GLP study is performed according to the OECD Guideline

Justification for selection of acute toxicity – dermal endpoint
There is only one study available

Justification for classification or non-classification