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EC number: 211-629-7 | CAS number: 676-58-4
Toxicity to aquatic algae and cyanobacteria
Administrative data
Link to relevant study record(s)
Description of key information
The test substance Methylmagnesium chloride was examined in a acute growth inhibition test for alga according OECD Guideline 201.The growth inhibitory ratio of Chlorella sp. was 1.73% and indicated that the EC50 (72h) was greater than highest tested nominal concentration of 100 mg/L. Highest nominal concentration is equivalent to analytical meassured 149.06 mg/L.
Key value for chemical safety assessment
Additional information
This study was conducted to assess the acute toxicity of Methylmagnesium chloride on single cell algae by observing acute inhibitory effects. The growth was observed and recorded at 24 h, 48 h and 72 h. Based on the results of preliminary test, the growth inhibitory ratio in solutions with 100 mg/L Methylmagnesium chloride was 0.86% and below 50%, it was not necessary to conduct the definitve test.
However limit test with 3 replicates was carried out. The growth inhibitory ratio was 1.73% and indicated that the EC50 (72h) was greater than 100 mg/L, which is equivalent to meassured 149.06 mg/L.
Atomic absorption spectrometry of test solutions was used to generate standard curve to read substance concentration directly at the beginning and the end of test (c(48h)/c(0h) = 89.6%)
Potassium dichromat was used as positive control. The calculated EC50 (72h) = 0.88 mg/L is in accordance with the accepted range of Guidline.
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