Registration Dossier
Registration Dossier
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EC number: 413-610-0 | CAS number: 124172-53-8 LICHTSCHUTZMITTEL 1736
Acute Toxicity: inhalation
Administrative data
- Endpoint:
- acute toxicity: inhalation
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
Data source
Reference
- Reference Type:
- other:
- Title:
- Unnamed
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 403 (Acute Inhalation Toxicity)
- GLP compliance:
- yes
- Limit test:
- yes
Test material
- Reference substance name:
- N,N'-1,6-hexanediylbis(N-(2,2,6,6-tetramethyl-piperidin-4-yl)formamide
- EC Number:
- 413-610-0
- EC Name:
- N,N'-1,6-hexanediylbis(N-(2,2,6,6-tetramethyl-piperidin-4-yl)formamide
- Cas Number:
- 124172-53-8
- Molecular formula:
- C26 H50 N4 O2
- IUPAC Name:
- N,N'-1,6-hexanediylbis(N-(2,2,6,6-tetramethyl-piperidin-4-yl)formamide
- Details on test material:
- Mass median aerodynamic diameter: 2.9 mµm
Constituent 1
Test animals
- Species:
- rat
- Strain:
- other: Wistar Chbb, THOM
- Sex:
- male/female
Administration / exposure
- Route of administration:
- inhalation: aerosol
- Type of inhalation exposure:
- nose/head only
- Vehicle:
- other: air, additive: Aerosil 1 wt%
- Duration of exposure:
- 4 h
- Concentrations:
- 5 mg/L
- No. of animals per sex per dose:
- 5
Results and discussion
Effect levels
- Sex:
- male/female
- Dose descriptor:
- LC50
- Effect level:
- > 5 mg/L air
- Exp. duration:
- 4 h
- Mortality:
- Male: 5 mg/L; Number of animals: 5; Number of deaths: 0
Female: 5 mg/L; Number of animals: 5; Number of deaths: 0 - Clinical signs:
- other: Accelerated breathing during exposure. Reddish incrustated noses (day 1 of observation period)
- Gross pathology:
- Without pathological findings.
Applicant's summary and conclusion
- Interpretation of results:
- not classified
- Remarks:
- Migrated information Criteria used for interpretation of results: EU
- Conclusions:
- No acute inhalational toxicity in rats.
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