Registration Dossier
Registration Dossier
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EC number: 264-261-4 | CAS number: 63469-23-8
Water solubility
Administrative data
Link to relevant study record(s)
- Endpoint:
- water solubility
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 2011-07-14 - 2011-07-15
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- EU Method A.6 (Water Solubility)
- Deviations:
- no
- GLP compliance:
- yes (incl. QA statement)
- Type of method:
- other: preliminary estimate
- Specific details on test material used for the study:
- No further details on test substance available
- Key result
- Remarks on result:
- other: During preliminary estimation, the sample was found to be miscible with water in all proportions.
- Details on results:
- An initial mass of 9.76 mg of test substance was added to 0.1 ml of water. The test substance was found to be completely miscible. More of the test substance was added up to 14100 mg in 1 ml of water with the sample being completely miscible in water. Temperature of measurement was not reported; ambient conditions are anticipated.
The miscibility was accompanied with evolution of heat (exothermic dissolution reaction). Sample solution turned deep yellow within 7 hours. No change in composition of test solution with time was confirmed (UV spectroscopy).
The solubility was therefore reported as "miscible" and no main study was performed. - Conclusions:
- The substance is concluded to be miscible with water in all proportions under ambient conditions.
Reference
Description of key information
The test substance was determined to be miscible with water in all proportions under ambient conditions, following a GLP study according to the preliminary test as specified in test method EC A.6 (Younis, 2011).
Key value for chemical safety assessment
- Water solubility:
- 100 g/L
- at the temperature of:
- 20 °C
Additional information
The substance is miscible with water in all proportions. The bounded value of 100 g/L is used as the key value for chemical safety assessment, being the maximum value for water solubility as defined in the EUSES program.
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