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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Toxicological information

Skin irritation / corrosion

Currently viewing:

Administrative data

Endpoint:
skin irritation: in vivo
Type of information:
migrated information: read-across based on grouping of substances (category approach)
Adequacy of study:
key study
Reliability:
2 (reliable with restrictions)

Data source

Reference
Title:
No information
Author:
Anonymous
Year:
2013
Bibliographic source:
OECD Toolbox v3.1

Materials and methods

Test guideline
Guideline:
other: read across (ECOSAR class neutral organics)
GLP compliance:
no

Test material

Constituent 1
Chemical structure
Reference substance name:
2,2-dimethoxy-1,2-diphenylethan-1-one
EC Number:
246-386-6
EC Name:
2,2-dimethoxy-1,2-diphenylethan-1-one
Cas Number:
24650-42-8
Molecular formula:
C16H16O3
IUPAC Name:
2,2-dimethoxy-1,2-diphenylethan-1-one

Results and discussion

In vivo

Results
Irritation parameter:
primary dermal irritation index (PDII)
Basis:
mean
Score:
1.2
Max. score:
8

Any other information on results incl. tables

See attached OECD Toolbox study for skin irritation/corrosion

Applicant's summary and conclusion

Interpretation of results:
not irritating
Remarks:
Migrated information Criteria used for interpretation of results: EU