Registration Dossier
Registration Dossier
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EC number: 202-439-5 | CAS number: 95-65-8
Ecotoxicological Summary
Administrative data
Hazard for aquatic organisms
Hazard for air
Hazard for terrestrial organisms
Hazard for predators
Additional information
Conclusion on classification
3,4-xylenol has a harmonised environmental classification of Aq. Chronic 2. At the time of assessing the harmonised classification (according to the former legislation, years before the CLP Regulation came into force), only data on fish (Pimephales promelas) and aquatic invertebrates (Daphnia magna and Crangon septemspinosa) were available for 3,4-xylenol.
- Short-term (acute) aquatic hazard:
LC50 fish (P. promelas): 14 mg/L
EC50 aquatic invertebrates (D. magna): 3.36 mg/L (NOACK, 2021) and 18.7 mg/L (Ecetox, 2019)
EC50 aquatic invertebrates (C. septemspinosa): 13.7 mg/L
ErC50 algae: 9.32 mg/L
No classification for Aq. Acute 1 is warranted. The LC50 for fish, EC50 for crustacea and ErC50 for algae are all > 1 mg/l.
- Long-term (chronic) aquatic hazard:
chronic toxicity data:
NOEC algae: 1.58 mg/L (based on growth rate inhibition)
acute toxicity data:
LC50 fish (P. promelas): 14 mg/L
EC50 aquatic invertebrates (D. magna): 3.36 mg/L (NOACK, 2021) and 18.7 mg/L (Ecetox, 2019)
EC50 aquatic invertebrates (C. septemspinosa): 13.7 mg/L
3,4-xylenol is predicted to be not readily biodegradable. Based on this prediction and the observed aquatic toxicity, an Aq. Chronic 2 classification is warranted (surrogate method: derivation of a chronic classification on the basis of an acute Ecotoxicity Reference value of 3.36 mg/L). This self-classification is in line with the Harmonised Classification as reported in Annex VI of the CLP-Regulation.
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