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EC number: 821-451-7 | CAS number: 78920-10-2
Water solubility
Administrative data
- Endpoint:
- water solubility
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 08 August 2018 - 17 October 2018
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
Cross-reference
- Reason / purpose for cross-reference:
- reference to other study
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 019
Materials and methods
Test guidelineopen allclose all
- Qualifier:
- according to guideline
- Guideline:
- EU Method A.6 (Water Solubility)
- Version / remarks:
- 2016
- Deviations:
- no
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 105 (Water Solubility)
- Version / remarks:
- 1995
- Deviations:
- no
- Qualifier:
- according to guideline
- Guideline:
- EPA OPPTS 830.7840 (Water Solubility)
- Version / remarks:
- 1998
- Deviations:
- no
- GLP compliance:
- yes
- Type of method:
- flask method
Test material
- Reference substance name:
- 5-hydroxy-4-propyl-2,5-dihydrofuran-2-one
- Cas Number:
- 78920-10-2
- Molecular formula:
- C7H10O3
- IUPAC Name:
- 5-hydroxy-4-propyl-2,5-dihydrofuran-2-one
- Test material form:
- liquid: viscous
- Details on test material:
- - Appearance: Brown viscous liquid
- Storage condition of test material: At room temperature
Constituent 1
Results and discussion
Water solubility
- Key result
- Water solubility:
- 121 g/L
- Conc. based on:
- test mat.
- Loading of aqueous phase:
- 540 g/L
- Incubation duration:
- >= 0 - <= 72 h
- Temp.:
- 20 °C
- pH:
- 2.9
- Remarks on result:
- other: reported value = corrected for purity
- Details on results:
- - The mean of the concentrations after 24, 48 and 72 h was reported as the water solubility of the substance.
- Maximum difference (24, 48 and 72 h) meets the criterion of ≤ 15% (i.e. 2.9%)
- No test item was detected in the pretreated sample from the blank.
Any other information on results incl. tables
Table: water solubility results (flask method)
Stirring time |
Analyzed concentration |
Mean |
Maximum difference |
pH |
|
|
|
|
|
24 |
120 |
121 |
2.9 |
2.9 |
|
|
|
|
|
48 |
124 |
|
|
|
|
|
|
|
|
72 |
120 |
|
|
|
|
|
|
|
|
reported concentrations are corrected for the purity of the test item
Applicant's summary and conclusion
- Conclusions:
- The water solubility of the substance at 20°C was determined to be 121 g/L (based on purity correction).
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