Registration Dossier
Registration Dossier
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EC number: 412-420-5 | CAS number: 133909-99-6 TRITYL-LOSARTAN; TRITYL-MK0954
Biodegradation in water: screening tests
Administrative data
- Endpoint:
- biodegradation in water: ready biodegradability
- Type of information:
- experimental study
- Adequacy of study:
- other information
- Reliability:
- 1 (reliable without restriction)
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
Materials and methods
Test guidelineopen allclose all
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 301 D (Ready Biodegradability: Closed Bottle Test)
- Qualifier:
- according to guideline
- Guideline:
- EU Method C.6 (Degradation: Chemical Oxygen Demand)
- GLP compliance:
- yes
Test material
- Reference substance name:
- 2-butyl-4-chloro-4,5-dihydro-5-hydroxymethyl-1-[2'-(2-triphenylmethyl-1,2,3,4-2H-tetrazol-5-yl)-1,1'-biphenyl-4-methyl]-1H-imidazole
- EC Number:
- 412-420-5
- EC Name:
- 2-butyl-4-chloro-4,5-dihydro-5-hydroxymethyl-1-[2'-(2-triphenylmethyl-1,2,3,4-2H-tetrazol-5-yl)-1,1'-biphenyl-4-methyl]-1H-imidazole
- Cas Number:
- 133909-99-6
- Molecular formula:
- C41H37ClN6O
- IUPAC Name:
- [2-butyl-4-chloro-1-({2'-[2-(triphenylmethyl)-2H-1,2,3,4-tetrazol-5-yl]-[1,1'-biphenyl]-4-yl}methyl)-1H-imidazol-5-yl]methanol
Constituent 1
Study design
- Inoculum or test system:
- activated sludge (adaptation not specified)
- Duration of test (contact time):
- 28 d
Results and discussion
% Degradationopen allclose all
- Value:
- 0
- Sampling time:
- 1 d
- Value:
- 0
- Sampling time:
- 5 d
- Value:
- 0
- Sampling time:
- 15 d
- Value:
- 1
- Sampling time:
- 28 d
BOD5 / COD results
BOD5 / COD
- Parameter:
- COD
- Value:
- 2.74 g O2/g test mat.
Any other information on results incl. tables
A separate BOD was not carried out.
From the Ready Biodegradability Test, the BOD at 5 days was -0.0275 g/g (-0.055 mg/l for a 2 mg/l solution at 5 days).
The COD was not determined. The theorical oxygen demand calculated for complete oxidation of nitrogen to nitrates was 2.74 g/g (5.49 mg O2/l for a 2 mg/l solution)
Applicant's summary and conclusion
- Validity criteria fulfilled:
- yes
- Interpretation of results:
- not inherently biodegradable
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