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Physical & Chemical properties

Water solubility

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Reference
Endpoint:
water solubility
Type of information:
experimental study
Adequacy of study:
key study
Study period:
18 May to 7 June 2017
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Qualifier:
according to guideline
Guideline:
OECD Guideline 105 (Water Solubility)
GLP compliance:
not specified
Type of method:
flask method
Key result
Water solubility:
1.265 g/L
Conc. based on:
test mat.
Incubation duration:
>= 24 - <= 72 h
Temp.:
20 °C
pH:
ca. 5.2

The concentrations of the different test solutions were calculated automatically using the equation of the calibration curve. The results are summarised in the table below:

Incubation time

[hours]

Experiment

Concentration

[mg/25 mL]

Average

[mg/25 mL]

72

A1

31.752

31.64

A2

31.531

48

B1

31.579

31.58

B2

31.575

24

C1

31.846

31.68

C2

31.514

 

These analytical results allow the calculation of the water solubility of the test item.

Incubation time

[hours]

Water Solubility

[g/L]

Average

[g/L]

24

1.267

1.265 ± 0.00208

48

1.263

72

1.266

 

The pH value of the sample solution was 5.24 (5.25, 5.19) after 24 (48, 72) hours of incubation.

Description of key information

Water solubility: 1.265 g/L at 20 °C, pH = 5.2 (OECD guideline 105, flask method)

Key value for chemical safety assessment

Water solubility:
1.265 g/L
at the temperature of:
20 °C

Additional information