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EC number: 946-001-8
CAS number: -
Initially, three females (Group 1) were treated at a dose level of 2000
mg/kg bw. As no mortality was observed, a confirmatory group (Group 2)
was treated at the same dose level. No mortality was observed in the
confirmatory group. Therefore, no further testing was required according
to OECD 423 and Commission Regulation (EC) No 440/2008 of 30 May 2008,
Deviations from the study plan:
Due to technical reasons, a relative humidity value (minimum of 26%)
outside the expected range of 30-70% was once recorded during the
acclimatisation period of the study. However, this minor difference of
the environmental parameter was considered not to have adversely
affected the results or integrity of the study as confirmed by the
During the formulation, the test item was weighed and the formulations
were prepared on a weight:volume basis (as (w/v)%) in the Pharmacy,
therefore adjustment for specific gravity of the vehicle was not made.
These deviations are considered not to have had an impact on the outcome
of the study and interpretation of the results.
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