Clorofene

Solubility in organic solvents / fat solubility

Link to relevant study record(s)

Reference

Endpoint:

solubility in organic solvents / fat solubility

Type of information:

experimental study

Adequacy of study:

key study

Study period:

2 July 2007 to 16 July 2007

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

guideline study

Qualifier:

according to guideline

Guideline:

other: CIPAC Handbook; Vol. F, MT 157 - Water solubility; Vol. H, MT 181 Solubility in organic solvents

Deviations:

not specified

GLP compliance:

yes (incl. QA statement)

Remarks:

Ministerium für Umwelt und Naturschutz, Landwirtschaft und Verbraucherschutz, Düsseldorf, Nordrheim-Westfalen, Germany

Key result

Medium:

methanol

Solubility:

> 250 g/L

Temp.:

10 °C

Key result

Medium:

methanol

Solubility:

> 250 g/L

Temp.:

20 °C

Key result

Medium:

methanol

Solubility:

> 250 g/L

Temp.:

30 °C

Key result

Medium:

toluene

Solubility:

> 250 g/L

Temp.:

10 °C

Key result

Medium:

toluene

Solubility:

> 250 g/L

Temp.:

20 °C

Key result

Medium:

toluene

Solubility:

> 250 g/L

Temp.:

30

Test substance stable:

yes

Final Result

The solubility of the test item Chlorophene in methanol and in toluene at 10 °C, 20 °C and 30 °C were > 250 g/L (visually checked in preliminary tests). Therefore it was not necessary to determine the exact value of the solubility of the test item in a main test.

Individual Results

Preliminary test at 10 °C

Solvent	Initial weight   [g]	Volume of solvent [mL]	Initial weight/volume [g/L]	Conclusion (solubility,firstestimate)
Methanol	1.79	5	264*	>250g/L
Toluene	1.82	5	267*	>250g/L

*Calculation of the clear solution:

Initial weight / (Initial weight + Volume of solvent)

Example for Methanol:

1.79 g * 1000 mL / (1.79g + 5 mL) = 264 g/L

Preliminary test at 20 °C

Solvent	Initial weight   [g]	Volume of solvent [mL]	Initial weight/volume [g/L]	Conclusion (solubility,firstestimate)
Methanol	1.80	5	265*	>250g/L
Toluene	1.91	5	276*	>250g/L

Preliminary test at 30 °C

Solvent	Initial weight   [g]	Volume of solvent [mL]	Initial weight/volume [g/L]	Conclusion (solubility,firstestimate)
Methanol	1.80	5	265*	>250g/L
Toluene	1.91	5	276*	>250g/L

Description of key information

Solubility in methanol is > 250 g/L at 10 ºC, 20 ºC, and 30 ºC; solubility in toluene is > 250 g/L at 10 ºC, 20 ºC, 30 ºC (CIPAC MT 157, CIPAC MT 181).