Registration Dossier
Registration Dossier
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EC number: 206-643-5 | CAS number: 361-09-1
Acute Toxicity: oral
Administrative data
- Endpoint:
- acute toxicity: oral
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 1985
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- data from handbook or collection of data
Data source
Reference
- Reference Type:
- review article or handbook
- Title:
- Acute oral toxicity in mouse
- Year:
- 1 985
- Bibliographic source:
- Eisei Shikenjo Hokoku. Bulletin of the Institute of Hygienic Sciences. Vol. (103), Pg. 29
Materials and methods
Test guideline
- Qualifier:
- no guideline available
- Principles of method if other than guideline:
- Acute oral toxicity in mouse
- GLP compliance:
- not specified
- Test type:
- other: not specified
Test material
- Reference substance name:
- Sodium cholate
- EC Number:
- 206-643-5
- EC Name:
- Sodium cholate
- Cas Number:
- 361-09-1
- Molecular formula:
- C24H40O5.Na
- IUPAC Name:
- sodium cholate
- Test material form:
- solid: crystalline
Constituent 1
Test animals
- Species:
- mouse
- Strain:
- not specified
- Sex:
- not specified
Administration / exposure
- Route of administration:
- other: oral, not specified
- Vehicle:
- not specified
Results and discussion
Effect levels
- Key result
- Sex:
- not specified
- Dose descriptor:
- LD50
- Effect level:
- 2 400 mg/kg bw
- Based on:
- not specified
Applicant's summary and conclusion
- Interpretation of results:
- Category 5 based on GHS criteria
- Conclusions:
- The acute oral LD50 for sodium cholate in mouse is 2400 mg/kg bw.
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