2-{3-[(4-amino-2-methylpyrimidin-5-yl)methyl]-4-methyl-1,3-thiazol-3-ium-5-yl}ethyl hydrogen phosphate

Oxidising properties

Link to relevant study record(s)

Reference

Endpoint:

oxidising solids

Type of information:

experimental study

Adequacy of study:

key study

Study period:

02 Sep - 09 Sep 2016

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

guideline study

Qualifier:

according to guideline

Guideline:

EU Method A.17 (Oxidising Properties (Solids))

Version / remarks:

adopted in 2008

Deviations:

no

GLP compliance:

no

Specific details on test material used for the study:

Storage conditions: Ambient temperature (10 to 30 °C)

Contact with:

powdered cellulose

Sample tested:

test mixture as specified

Remarks:

test item and cellulose 2:1

Parameter:

preliminary test

Remarks on result:

mixture does not ignite and burn

Remarks:

Only local charring seen

Sample tested:

test mixture as specified

Remarks:

barium nitrate/cellulose 2:1

Parameter:

preliminary test

Remarks on result:

other: 3 test mixtures burned down completely in 68, 64 and 70 s

Sample tested:

reference mixture as specified

Remarks:

barium nitrate with cellulose with different wt. % oxidizer

Parameter:

maximum burning rate

Result:

1.34 mm/s

Remarks on result:

other: result found for mixture with 55 wt. % oxidizer

Sample tested:

test mixture as specified

Remarks:

cellulose with 10 wt % test item

Parameter:

burning time of reaction over a distance of 200 mm

Remarks on result:

other: mixture extinguished in preliminary burning phase

Sample tested:

test mixture as specified

Remarks:

cellulose with 20, 30, 60, 90 wt % test item

Parameter:

burning time of reaction over a distance of 200 mm

Remarks on result:

other: mxiture could not be ingited, only local charring seen

Results
Preliminary test
Three test mixtures of test item and cellulose 2:1 did not burn, they showed local charring in contact with the ignition source.
Three test mixtures of barium nitrate/cellulose 2.1 burned down completely in 68, 64 and 70 s, respectively.

Main Test
Four tests were done for the reference mixture (barium nitrate and cellulose) with 50, 55, 60 and 70 wt. % oxidizer (barium nitrate).

Table 1 – Burning times and rates of reference mixtures

Barium nitrate [wt. %]	Burning time over 200 mm [s]	Burning rate [mm/s]
50	196	1.02
55	149	1.34
60	152	1.32
70	206	0.97

The highest burning rate of 1.34 mm/s was found for the mixture with 55 wt. % oxidizer.

Mixtures of test item with cellulose were prepared in between 10 and 90 wt. % of the test item (Table 2).

Table 2 – Burning times and rates of test item mixtures

Test item [%]	Burning time over 200 mm [s]	Burning rate [mm/s]
10	Mixture extinguished in the preliminary burning phase	---
20	Mixture could not be ignited, only local charring was seen.
30
60
90

 

As the maximum burning rate of the test item and cellulose mixtures did not burn and is much lower than the maximum burning rate of the reference mixture, the “fastest” mixtures were only repeated twice to verify these values (Table 3 ).

Table 3 – Burning times and rates of fastest test item mixtures

Test	t [s]	V [mm/s]	t [s]	V [mm/s]	t [s]	V [mm/s]
10%	Mixture extinguished in the preliminary burning phase.
20%	Mixture could not be ignited, only local charring seen.
30%

 

Discussion
The behavior upon contact with the ignition flame was the same as in the first test for all mixtures (Table 2 ). No propagation over the burning distance could be seen.

The maximum burning rate of test item and cellulose mixtures was lower than that of the reference mixture of cellulose with barium nitrate (1.34 mm/s).

Conclusion
The test item has no oxidizing properties.

Description of key information

Non oxidizing solid (EU Method A.17.)

Key value for chemical safety assessment

Oxidising properties:

non oxidising

Additional information

No propagation over the burning distance was seen. The maximum burning rate of test item and cellulose mixtures was lower than that of the reference mixture of cellulose with barium nitrate (1.34 mm/s).

Justification for classification or non-classification

The available data on oxidizing properties of the test substance do not meet the criteria for classification according to Regulation (EC) 1272/2008 or Directive 67/548/EEC, and are therefore conclusive but not sufficient for classification: The maximum burning rate of the test mixture was less than that of the reference mixture (barium nitrate and cellulose 2:1) in a test according to the EU method A.17.