Registration Dossier
Registration Dossier
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EC number: 247-499-3 | CAS number: 26172-54-3
Particle size distribution (Granulometry)
Administrative data
- Endpoint:
- particle size distribution (granulometry)
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- September 2017 to January 2018
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 018
- Report date:
- 2018
Materials and methods
Test guidelineopen allclose all
- Qualifier:
- according to guideline
- Guideline:
- other: CIPAC MT 187
- Deviations:
- no
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 110 (Particle Size Distribution / Fibre Length and Diameter Distributions - Method A: Particle Size Distribution (effective hydrodynamic radius)
- Deviations:
- no
- Qualifier:
- according to guideline
- Guideline:
- ISO 13320 (Particle size analysis - Laser diffraction methods)
- Principles of method if other than guideline:
- Laser diffraction
- GLP compliance:
- yes (incl. QA statement)
- Type of method:
- Laser scattering/diffraction
- Type of particle tested:
- primary particle
- Type of distribution:
- volumetric distribution
Test material
- Reference substance name:
- 2-Methyl-4-Isothiazolin-3-One Hydrochloride
- Cas Number:
- 26172-54-3
- Molecular formula:
- C4H5NOS.HCl
- IUPAC Name:
- 2-Methyl-4-Isothiazolin-3-One Hydrochloride
- Test material form:
- solid
- Details on test material:
- MIT.HCl as manufacured has a purity of >99.9% therefore the technical grade and analytical grade are identical
Constituent 1
- Specific details on test material used for the study:
- Batch Number 10013913, Purity >99.9%, Expiry Date 30 November 2018
Analytical grade and technical grade material are identical
Results and discussion
- Mass median aerodynamic diameter:
- ca. 105 µm
- Geometric standard deviation:
- ca. 3.7
Particle size
- Key result
- Percentile:
- D50
- Mean:
- ca. 105.4 µm
- St. dev.:
- 3.7
Applicant's summary and conclusion
- Conclusions:
- The median particle size L50 of the test item deduced from the particle size distributions was:
105.0 µm.
The GSD deduced from these distributions was:
σg = 3.7
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