Potassium nitrite

Density

Link to relevant study record(s)

Reference

Endpoint:

density, other

Remarks:

density

Type of information:

experimental study

Adequacy of study:

key study

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

guideline study

Justification for type of information:

Experimental test result performed using standard test guidelines

Qualifier:

according to guideline

Guideline:

OECD Guideline 109 (Density of Liquids and Solids)

Qualifier:

according to guideline

Guideline:

other: according to the method recommended in the International Pharmacopoeia, fourth Edition, 2014

GLP compliance:

no

Type of method:

pour and tap (for solids)

Key result

Type:

pour density

Density:

0.834 g/cm³

Temp.:

27.6 °C

Remarks on result:

other: At 970.5 hPa.

Key result

Type:

tap density

Density:

0.87 g/cm³

Temp.:

27.6 °C

Remarks on result:

other: At 970.5 hPa.

Method Details		Observations		Remarks if, any
Guideline	OECD 109	1^stReading	2^ndReading
Method	Test methods: Pour density and tapped density of powders”recommended inThe International Pharmacopoeia, Fourth Edition, 2014[1]
Principle of method	Pour Density:It is the ratio of known weight of test item and its volume in graduated glass cylinder. Tap Density:It is the difference between the volume of test item measured before & after tapping in the graduated glass cylinder.
Test temperature (°C)	-	26.6°C	28.6°C
Atmospheric pressure (in hPa)	-	970.9	970.2
Weight of test item(m)		20.010 g	20.009 g
Volume of measuring cylinder; readability in g		50 ml; 2 ml	50 ml; 2 ml
Volume of test item without tapping (V)		24 ml	24 ml
Volume of test item after tapping ( V1)	After 10 tapping	23 ml	23 ml
	After 50 tapping	23 ml	23 ml
	After 100 tapping	-	-
	After 250 tapping	------	-------
	After 500 tapping	--------	------
	After 750 Tapping	--------	------

Conclusions:

The density of test chemical was determined following OECD guideline 109 and according to the method recommended in the International Pharmacopoeia, fourth Edition. The pour density and tapped density of the test chemical was determined to be 0.8337 g/cm³ and 0.8699 g/cm³at 27.6°C and 970.5 hPa.

Executive summary:

Based on the available data from study report, the density of test chemical was determined following OECD guideline 109 and according to the method recommended in the International Pharmacopoeia, fourth Edition. The pour density and tapped density of the test chemical was determined to be 0.8337 g/cm³ and 0.8699 g/cm³at 27.6°C and 970.5 hPa.

Description of key information

In an experimental study from study report, the density of test chemical was determined following OECD guideline 109 and according to the method recommended in the International Pharmacopoeia, fourth Edition. The pour density and tapped density of the test chemical was determined to be 0.8337 g/cm³ and 0.8699 g/cm³at 27.6°C and 970.5 hPa.

Key value for chemical safety assessment

Relative density at 20C:

0.834

Additional information

In an experimental study from study report, the density of test chemical was determined following OECD guideline 109 and according to the method recommended in the International Pharmacopoeia, fourth Edition. The pour density and tapped density of the test chemical was determined to be 0.8337 g/cm³ and 0.8699 g/cm³at 27.6°C and 970.5 hPa.

From authoritative database and secondary source, the density of test chemical was determined to be 1.92 g/cm3 at 20°C.

In a supporting study from various reliable sources, the density of test chemical was determined to be 1.915 g/cm3.