Registration Dossier
Registration Dossier
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EC number: 903-982-7 | CAS number: -
Acute Toxicity: oral
Administrative data
- Endpoint:
- acute toxicity: oral
- Type of information:
- experimental study
- Adequacy of study:
- supporting study
- Study period:
- 1975
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- study well documented, meets generally accepted scientific principles, acceptable for assessment
- Remarks:
- A scientific review (peer reviewed). No data on GLP.
Data source
Referenceopen allclose all
- Reference Type:
- review article or handbook
- Title:
- Unnamed
- Year:
- 2 008
- Reference Type:
- review article or handbook
- Title:
- Unnamed
- Year:
- 1 976
Materials and methods
- Principles of method if other than guideline:
- -principle of test: Ten rats received single oral doses of 5.0 g/kg test material each. Animals were observed for 14 days. No details on the method.
- Test type:
- acute toxic class method
Test material
- Reference substance name:
- 3,3-dimethyl-8,9-dinorbornan-2-yl acetate
- EC Number:
- 237-588-5
- EC Name:
- 3,3-dimethyl-8,9-dinorbornan-2-yl acetate
- Cas Number:
- 13851-11-1
- Molecular formula:
- C12H20O2
- IUPAC Name:
- 1,3,3-trimethylbicyclo[2.2.1]hept-2-yl acetate
Constituent 1
Test animals
- Species:
- rat
- Sex:
- not specified
Administration / exposure
- Route of administration:
- oral: unspecified
- Doses:
- 5000 mg/kg bw
- No. of animals per sex per dose:
- 10 animals
- Control animals:
- not specified
- Details on study design:
- Animals were observed for 14 days
Results and discussion
Effect levels
- Sex:
- not specified
- Dose descriptor:
- LD50
- Effect level:
- > 5 000 mg/kg bw
- Based on:
- test mat.
- Mortality:
- Two animals died (2/10).
- Clinical signs:
- No adverse clinical signs were observed
Applicant's summary and conclusion
- Interpretation of results:
- other: Not classified (CLP Regulation EC no. 1272/2008)
- Conclusions:
- Oral LD50 (rats) is greater than 5000 mg/kg bw.
- Executive summary:
The acute oral LD50 of fenchyl acetate was reported to exceed 5000 mg/kg bw. Ten rats received single oral doses of 5.0 g/kg test material each. Animals were observed for 14 days. Two animals died (2/10). No adverse clinical signs were observed.
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