Resinoid of Liquidambar styraciflua (Hamamelidaceae) obtained from exudate by organic solvents extraction

Surface tension

Administrative data

Endpoint:

surface tension

Data waiving:

study scientifically not necessary / other information available

Justification for data waiving:

the study does not need to be conducted because based on structure, surface activity is not expected or cannot be predicted

the study does not need to be conducted because surface activity is not a desired property of the material

Justification for type of information:

JUSTIFICATION FOR DATA WAIVING
In accordance with column 2 of REACh Annex VII, the study needs only to be conducted if based on structure, surface activity is expected or can be predicted.
The present substance is not intended to be used as a surfactant (i.e. not a desired property), and known constituents (mainly aromatic esters) do not contain groups (such as distinct polar and non-polar parts) indicating that it will have surface-active properties in solution. Therefore, the study is deemed unnecessary.
Moreover, some of major constituents have an estimated water solubility < 1 mg/L (at 25°C), which supports that the test does not need to be conducted.

Cross-reference

Reason / purpose for cross-reference:

data waiving: supporting information

Reference

The registered UVCB substance is considered to have low water solubility (< 1 mg/L), based on the less soluble of major constituents, having Wsol in the range 0.30 to 8042 mg/L at 25°C (QSAR calculated values).

No experimental study was conducted on the test substance. Instead, a constituent-based, Weigh-of-Evidence approach, was performed.

The solubility of the registered UVCB substance as a whole will be limited by the less soluble constituent:

Five major constituents were targeted, > 1% each and representing 60% of a typical composition. No published data was available, so predictions were calculated with two EpiSuite models, and found in the range between 0.30 and 8042 mg/L. As anticipated from structures, esters were of low solubility (0.30 - 26 mg/L), while polar constituents (acids, alcohols) were more soluble (570 - 8042 mg/L).

No single key value was derived for the UVCB substance, result expressed as a range was prefered, having more scientific sense.

As a qualitative assessement, the substance as a whole is regarded as having low water solubility, based on less soluble constituents.

Moreover, it should be highlighted that for such a substance (i.e. containing both non-polar and polar constituents), the composition of the dissolved fraction will depend on the loading rate.