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EC number: 229-043-5 | CAS number: 6407-78-9
Endpoint summary
Administrative data
Description of key information
Adsorption / desorption
KOCWIN model (v2.00) of Estimation Programs Interface (EPI Suite, 2017) was used to predict the soil adsorption coefficient i.e Koc value of test chemical 4 -[(E)-2 -(2,4 -dimethylphenyl) diazen-1 -yl]-3 -methyl-1 -phenyl-4,5 -dihydro-1H-pyrazol-5 -one (CAS no. 6407 -78 -9). The soil adsorption coefficient i.e Koc value of 4 -[(E)-2 -(2,4 -dimethylphenyl)diazen-1 -yl]-3 -methyl-1 -phenyl-4,5 -dihydro-1H-pyrazol-5-one was estimated to be 14680 L/kg (log Koc=4.1669) by means of MCI method (at 25 deg C). This Koc value indicates that the substance 4-[(E)-2 -(2,4-dimethylphenyl)diazen-1-yl]-3-methyl-1-phenyl-4,5-dihydro-1H-pyrazol-5-one has a strong sorption to soil and sediment and therefore have negligible to slow migration potential to ground water.
Additional information
Adsorption / desorption
Various predicted data for the target compound 4-[(E)-2-(2,4-dimethylphenyl)diazen-1-yl]-3-methyl-1-phenyl-4,5-dihydro-1H-pyrazol-5-one (CAS No. 6407-78-9) were reviewed for the adsorption end point which are summarized as below:
In aprediction done using theKOCWIN Program(v2.00) of Estimation Programs Interface (EPI Suite, 2017) was used to predict the soil adsorption coefficient i.e Koc value of test chemical 4 -[(E)-2 -(2,4 -dimethylphenyl) diazen-1 -yl]-3 -methyl-1 -phenyl-4,5 -dihydro-1H-pyrazol-5 -one (CAS no. 6407 -78 -9). The soil adsorption coefficient i.e Koc value of 4 -[(E)-2 -(2,4 -dimethylphenyl)diazen-1 -yl]-3 -methyl-1 -phenyl-4,5 -dihydro-1H-pyrazol-5-one was estimated to be 14680 L/kg (log Koc=4.1669) by means of MCI method (at 25 deg C). This Koc value indicates that the substance 4-[(E)-2 -(2,4-dimethylphenyl)diazen-1-yl]-3-methyl-1-phenyl-4,5-dihydro-1H-pyrazol-5-one has a strong sorption to soil and sediment and therefore have negligible to slow migration potential to ground water.
In a supporting study from secondary source (Environment Canada (EC) Health Canada (HC), 2016), adsorption study was conducted for estimating the adsorption coefficient (Koc) value of test chemical 4 -[(E)-2 -(2,4 -dimethylphenyl)diazen-1 -yl]-3 -methyl-1 -phenyl-4,5 -dihydro-1H- pyrazol-5 -one (CAS no.6407 -78 -9). The adsorption coefficient (Koc) value was calculated using a model. The adsorption coefficient (Koc) value of test substance 4 -[(E)-2 -(2,4 -dimethylphenyl)diazen-1 -yl]-3 -methyl-1 -phenyl-4,5 -dihydro-1H-pyrazol-5-onewas estimated to be 31622.77 dimensionless (Log Koc = 4.5). This Koc value indicates that the substance 4 -[(E)-2 -(2,4 -dimethylphenyl)diazen-1-yl]-3-methyl-1-phenyl-4,5-dihydro-1H-pyrazol-5-one has a very strong sorption to soil and sediment and therefore have negligible migration potential to ground water.
On the basis of above overall results for target chemical 4 -[(E)-2-(2,4-dimethylphenyl)diazen-1-yl]-3-methyl-1-phenyl-4,5-dihydro-1H-pyrazol-5-one (from EPI suite,2017 and secondary source, 2016), it can be concluded that the Koc value of test substance 4-[(E)-2-(2,4-dimethylphenyl)diazen-1-yl]-3-methyl-1-phenyl-4,5-dihydro-1H-pyrazol-5-one ranges from 14680–31622.77,indicating that the test chemical 4-[(E)-2-(2,4-dimethylphenyl)diazen-1-yl]-3-methyl-1-phenyl-4,5-dihydro-1H-pyrazol-5-one has a strong to very strong sorption to soil and sediment and therefore have slow to negligible migration potential to ground water.
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