Registration Dossier
Registration Dossier
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EC number: 212-849-6 | CAS number: 873-69-8
Boiling point
Administrative data
- Endpoint:
- boiling point
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 2017-01-05 - 2017-01-12 (experimental phase)
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 017
- Report date:
- 2017
Materials and methods
Test guidelineopen allclose all
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 103 (Boiling Point)
- Version / remarks:
- OECD Guideline No. 103 “Boiling Point“, dated 27. Jul. 1995
- Deviations:
- no
- Qualifier:
- according to guideline
- Guideline:
- EU Method A.2 (Boiling Temperature)
- Version / remarks:
- EU-Method A.2 dated 31. May 2008, “Boiling Temperature“
- Deviations:
- no
- GLP compliance:
- yes (incl. QA statement)
- Remarks:
- Landesamt für Umwelt, Wasserwirtschaft und Gewerbeaufsicht, Kaiser-Friedrich-Straße 7, 55116 Mainz, Germany
- Type of method:
- differential scanning calorimetry
Test material
- Reference substance name:
- Pyridine-2-carbaldehyde oxime
- EC Number:
- 212-849-6
- EC Name:
- Pyridine-2-carbaldehyde oxime
- Cas Number:
- 873-69-8
- Molecular formula:
- C6H6N2O
- IUPAC Name:
- pyridine-2-carbaldehyde oxime
- Test material form:
- solid: particulate/powder
Constituent 1
- Specific details on test material used for the study:
- STABILITY AND STORAGE CONDITIONS OF TEST MATERIAL
- Storage condition of test material: The test item was stored in a closed vessel at room temperature (15.8 – 24.4°C).
Results and discussion
Boiling point
- Key result
- Atm. press.:
- ca. 1 013.25 mBar
- Decomposition:
- yes
- Decomp. temp.:
- 225.08 °C
- Remarks on result:
- other:
- Remarks:
- mean of three determinations
Applicant's summary and conclusion
- Conclusions:
- The study was performed according to the OECD TG103 and EU Method A.2 (GLP) without deviations and therefore considered to be of the highest quality (reliability Klimisch 1). Differential scanning calorimetry is a scientifically reasonable method to determine not only the boiling point of a substance but also its melting point or decomposition temperature. There is no reason to believe that the results are not reliable. Two events were detected. As first event the melting point was determined with 113.46 ± 0.07 °C (386.61 ± 0.07 K), as second event the beginning decomposition of the test item was determined with 225.08 °C (498.23 K). Therefore, no boiling point could be determined.
- Executive summary:
The determination of the boiling point of pyridine-2-carbaldehyde oxime was performed via DSC (differential scanning calorimetry) in a OECD TG 103 study under GLP.
Two events were detected.
As first event the melting point was determined with:
113.46 ± 0.07 °C (386.61 ± 0.07 K)
As second event the beginning decomposition of the test item was determined with:
225.08 °C (498.23 K)
Therefore, no boiling point could be determined.
These values are the results of three independent determinations.
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