Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 201-184-7 | CAS number: 79-19-6
Endpoint summary
Administrative data
Description of key information
Key study: Test substance was tested for bioacumulation. Bioacumulation factor was found to be less than or equal to 3.8 - 4.2 L/kg in the concentration 0.4 mg/L and 39 L/kg in the concentration of 0.04 mg/L.
Additional information
Key study: According the OECD TG305 C and following GLP principles.
Semicarbazide hydrochloride was tested for bioacumulation in the fish species Cyrpinus Carpio.They were fed twice per week with pellets during the 6 weeks of treatment and allocated in water bowl. Before the test, the range finding study was carried out on the Rice fish (Oryziaslatipes, weighted 0.28 g) to find out the concentration of the test substance in the study. The evaluated LC 50 vale was LC50 (48 h)=80.1 mg/L. Test substance was dissolved. The solution was introduced into aquarium where fish were kept. The Dissolved oxygen concentration and temperature were analyzed. The concentrations of chemicals were analyzed and the bioconcentration factor was calculated. In the concentration of 0.4 mg/L of test substance, the BCF factor was less than or equal to 3.8 - 4.2 L/kg and in the concentration of 0.04 mg/L the BCF factor was 39 L/kg.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
