Registration Dossier
Registration Dossier
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EC number: 229-246-9 | CAS number: 6448-96-0
Endpoint summary
Administrative data
Description of key information
Biodegradation in water
Estimation Programs Interface Suite (2018) was run to predict the biodegradation potential of the test chemical in the presence of mixed populations of environmental microorganisms. The biodegradability of the substance was calculated using seven different models such as Linear Model, Non-Linear Model, Ultimate Biodegradation Timeframe, Primary Biodegradation Timeframe, MITI Linear Model, MITI Non-Linear Model and Anaerobic Model (called as Biowin 1-7, respectively) of the BIOWIN v4.10 software. The results indicate that test chemical is expected to be not readily biodegradable.
Additional information
Biodegradation in water
Predicted data of the test chemical and various supporting studies for its structurally similar read across substance were reviewed for the biodegradation end point which are summarized as below:
In a prediction done using Estimation Programs Interface Suite (2018), the biodegradation potential of the test chemical in the presence of mixed populations of environmental microorganisms was predicted. The biodegradability of the substance was calculated using seven different models such as Linear Model, Non-Linear Model, Ultimate Biodegradation Timeframe, Primary Biodegradation Timeframe, MITI Linear Model, MITI Non-Linear Model and Anaerobic Model (called as Biowin 1-7, respectively) of the BIOWIN v4.10 software. The results indicate that test chemical is expected to be not readily biodegradable.
In a supporting weight study from authoritative database (J-CHECK, 2010), biodegradation experiment was conducted for 14 days for evaluating the percentage biodegradability of test chemical. Concentration of inoculum i.e, sludge is 30 mg/l and initial test substance conc. used in the study is 100 mg/l. The percentage degradation of test chemical was determined to be 5.4% by in 14 days. On the basis of percent biodegradability value it is concluded that the test chemical is not readily biodegradable in water.
For the test chemical, biodegradation study was conducted by taking activated sludge as inoculums at 30 mg/L concentration. Biodegradation was analysed by using BOD parameter .The initial concentration of test chemical used was 100 mg/L. The test chemical showed 0 % biodegradability by BOD parameter by using activated sludge as inoculum in 14 days. On the basis of percent biodegradability it is concluded that test chemical is not readily biodegradable.
On the basis of above overall results of test chemical, it can be concluded that the test chemical can be considered to be not readily biodegradable in nature.
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