Registration Dossier
Registration Dossier
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EC number: 609-222-8 | CAS number: 3625-82-9
Hydrolysis
Administrative data
Link to relevant study record(s)
Description of key information
3-Methoxy-18-methyl-1,3,5(10)-estratrien-17 beta-ol is hydrolytically stable with half-lives at 25 °C > 1 year at pH 4, 7 and 9.
Key value for chemical safety assessment
- Half-life for hydrolysis:
- 1 yr
- at the temperature of:
- 25 °C
Additional information
3-Methoxy-18-methyl-1,3,5(10)-estratrien-17 beta-ol is a chiral compound (D-enantiomer). The hydrolytical behavior of the substance was experimentally investigated by the results of a hydrolysis study with the racemic mixture ethyltrienol. As, except in chiral environment, D-enantiomer and racemate should show the same behavior, hydrolytic stability is also expected for 3-Methoxy-18 -methyl-1,3,5(10)-estratrien-17 beta-ol is a chiral compound.
Therefore the substance can be considered as hydrolytically stable in the pH range 2-10, which is of relevance for biological systems.Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
