Registration Dossier
Registration Dossier
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EC number: 442-640-7 | CAS number: -
Adsorption / desorption
Administrative data
Link to relevant study record(s)
Description of key information
The adsorption coefficient (log Koc) of the test substance was determined according to EU method C.19. and OECD guideline 121 in compliance with GLP. Under the test conditions, the logarithmic adsorption coefficient (log Koc) of the test substance was determined to be 0.75, corresponding to a Koc of 5.62.
Key value for chemical safety assessment
- Koc at 20 °C:
- 5.62
Additional information
A study was performed to determine the adsorption coefficient (log Koc) of the test substance according to EU Method C.19. and OECD Guideline 121 in compliance with GLP.
Test was conducted using the HPLC method. The dead time was determined by using a "dead time marker". For calibration the retention times of a series of substances with known adsorption coefficients were measured and a calibration graph was established. The adsorption coefficient of the test substance was derived from its retention time and the calibration graph. Calibration and test substance measurement was run two series, respectively. Measurement 1 resulted in a log Koc value of 0.80, measurement 2 in a log Koc value of 0.69. The corresponding mean value is 0.75 with a standard deviation of 0.08.
Under the test conditions employed the logarithmic adsorption coefficient (log Koc) of the test substance was determined to be 0.75, corresponding to a Koc of 5.62.
[LogKoc: 0.75]
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