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EC number: 940-683-0 | CAS number: -
Short-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
Description of key information
The 48h acute toxicity of Esterol A to Daphnia magna was studied following OECD 202 guideline. The solution tested correspond to a saturated solution in accordance with WAF preparation procedure. No effects to Daphnia magna were observed at nominal concentration of 100%, 45.5%, 20.7%, 9.4%, 4.3%, 1.9% and 0 % of a stock solution saturated with a 5 mg/l of Esterol A. The actual concentration of the test substance was below the detection limit, so the concentration could not be measured.
Key value for chemical safety assessment
Fresh water invertebrates
Fresh water invertebrates
- Effect concentration:
- 0.13 mg/L
Additional information
The 48h acute toxicity of Esterol A toDaphnia magnawas studiedfollowing the 202 OECD guideline for testing of chemicalsunder static conditions.
The solution tested correspond to a saturated solution in accordance with WAF preparation procedure.
Daphnids were exposed during 48h to the test substance at nominal concentration of 100%, 45.5%, 20.7%, 9.4%, 4.3%, 1.9% and 0 % of a stock solution saturated with a 5 mg/l of Esterol A. As the substance tested is made through a WAF, only the results obtained with the saturated solution can be used for the toxicity evaluation (WAF cannot be diluted as prescribed in the "guidance document on aquatic toxicity testing of difficult substances and mixture" ). Therefore only the results obtained with the saturated solution (i.e. stock solution) will be considered as relevant. Considering the low water solubility of the substance, the concentration was measured by gas chromatography. Even in the saturated solution,the concentration measured was below detection limit of the GC method (0.13 mg/l).
In the tested conditionsnoimmobilizationof daphnids was observed after 24h nor 48h. The48h- EC50< 0.13 mg/l.
This study is classified as reliable with restrictions. It satisfies the guideline requirements for an acute toxicity study with freshwater invertebrates except for the stability of the substance that could not have been evaluated due to the concentration below detection limit of the analytical method.
Based on the results of this study,Esterol A is considered as not dangerous for daphnids up to its limit of solubility in the test medium. The exact concentration with no effect observed cannot be determined.
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