Registration Dossier
Registration Dossier
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EC number: 292-771-7 | CAS number: 90990-10-6
Biodegradation in water: screening tests
Administrative data
Link to relevant study record(s)
Description of key information
Key value for chemical safety assessment
- Biodegradation in water:
- readily biodegradable
Additional information
Since no study on ready biodegradability is available for fatty acids, C12-C14, read across from the key studies of lauric acid (C12, CAS 143-07-7) was done as well as QSAR predictions on ready biodegradability of myristic acid (C14, CAS 544-63-8).
Two biodegradability tests are available for lauric acid indicating ready biodegradability. Richterich and Mühlenberg (2001) conducted a closed bottle test according to OECD 301D. Under the test conditions, 86% oxygen consumption at a substance concentration of 2 mg/L and 62% at 5 mg/L were observed. The 10-day window was identified. In the short summary of Geisel and Berger (1998), the biodegradability was tested according to EU Method C.4 –E. The test also showed lauric acid to be readily biodegradable (85% within 30d at 2 mg/L of test substance and > 55% at 5 mg/L of test substance, passing 10-day window). Thus, lauric acid is readily biodegradable.
Results of the QSAR model BIOWIN v.4.10 (EPI Suite, 2012) predicts ready biodegradability for myristic acid. This method is based on the application of Bayesian analysis to ready biodegradation data for chemicals, derived collectively from all six OECD301 test methods plus OECD310.
Overall, the substance fatty acids, C12-C14 is regarded as readily biodegradable. This judgment is consistent with the hazard assessment presented in the OECD SIDS (2009) for the category “Aliphatic Acids Category” where aliphatic fatty acids with a carbon chain length in the range of C8 – C22 were judged to be readily biodegradable.
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