Registration Dossier
Registration Dossier
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EC number: 217-007-1 | CAS number: 1719-58-0
Short-term toxicity to fish
Administrative data
Link to relevant study record(s)
Description of key information
(96 h) LC50: 271 mg/l, O. mykiss (read-across from CAS 1066-40-6)
Key value for chemical safety assessment
Fresh water fish
Fresh water fish
- Effect concentration:
- 271 mg/L
Additional information
There are no reliable short-term fish toxicity data available for chlorodimethyl(vinyl)silane (CAS 1719-58-0). In water, chlorodimethyl(vinyl)silane hydrolyses very rapidly to dimethyl(vinyl)silanol, therefore good quality data for an appropriate structural analogue of this silanol, trimethylsilanol (CAS 1066-40-6), have been read across. The other hydrolysis product is hydrogen chloride.
A 96-hour LC50 value of 271 mg/l and a NOEC of 128 mg/l have been determined for the effects of trimethylsilanol on mortality of Oncorhynchus mykiss based on mean measured concentrations.
The potential for toxicity caused by the vinyl group has also been considered. Data for trimethoxyvinylsilane (CAS 2768-02-7) indicate that the vinyl fraction of the registered substance is of very low short-term toxicity to freshwater fish (96-h LC50 191 mg/l).
Refer to the discussion in the Section 6 endpoint summary for further discussion of the approach to chemical safety assessment for this registration substance, and justification for read-across used.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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