Registration Dossier
Registration Dossier
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EC number: 246-770-3 | CAS number: 25265-71-8
Toxicity to other aquatic organisms
Administrative data
- Endpoint:
- toxicity to other aquatic vertebrates
- Type of information:
- experimental study
- Adequacy of study:
- supporting study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: Published in peer-reviewed literature, adequate for assessment
Data source
Reference
- Reference Type:
- publication
- Title:
- Toxicity of mixtures of heavy metals and petrochemicals to xenopus laevis
- Author:
- de Zwart D. and Sloof W.
- Year:
- 1 987
- Bibliographic source:
- Bull. Environ. Contam. Toxicol. 38, pp 345-351
Materials and methods
- Principles of method if other than guideline:
- No data available
- GLP compliance:
- not specified
Test material
- Reference substance name:
- Oxydipropanol
- EC Number:
- 246-770-3
- EC Name:
- Oxydipropanol
- Cas Number:
- 25265-71-8
- Molecular formula:
- C6H14O3
- IUPAC Name:
- 1,1-Oxydi-2-Propanol
- Details on test material:
- Analytical grade dipropylene glycol
Constituent 1
Sampling and analysis
- Analytical monitoring:
- no
Test solutions
- Vehicle:
- not specified
Test organisms
- Test organisms (species):
- Xenopus laevis
- Details on test organisms:
- 3-4 weeks old
Study design
- Water media type:
- freshwater
- Limit test:
- no
- Total exposure duration:
- 48 h
Test conditions
- Test temperature:
- 20 ± 1 °C
- Salinity:
- Not applicable
- Details on test conditions:
- 10 randomly selected specimens of 3-4 wk old larvae were exposed in covered all-glass aquaria containing 1 litre of Dutch Standard Water. Nominal amounts of the test solutions were added only once at the beginning of the experiments. The test were performed singularly with a minimum of 5 concentrations levels having a factorial difference of 1.5. Mortality was recorded after 48 hours.
- Reference substance (positive control):
- not specified
Results and discussion
Effect concentrations
- Duration:
- 48 h
- Dose descriptor:
- LC50
- Effect conc.:
- 3 181 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- mortality
Applicant's summary and conclusion
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
