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Diss Factsheets

Physical & Chemical properties

Particle size distribution (Granulometry)

Administrative data

Endpoint:
particle size distribution (granulometry)
Type of information:
experimental study
Adequacy of study:
key study
Study period:
24 September 2009
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: Study performed according to company guideline, similar to draft EU method

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2009
Report date:
2009

Materials and methods

Test guideline
Qualifier:
equivalent or similar to guideline
Guideline:
other: EU 20268
Principles of method if other than guideline:
Ciba method SOP-24b (laser diffraction, dry measurement). This method is comparable to the draft guidance document EUR 20268 (2002, part 5.2 ¿Laser scattering/diffraction¿ for ¿Particle Size Distribution, Fibre Length and Diameter Distribution¿, European Commission, Directorate General JRC) (http://ecb.jrc.ec.europa.eu/documents/Testing-Methods/Guidance_Document_on_Granulometry.pdf)
Type of distribution:
volumetric distribution

Test material

Constituent 1
Chemical structure
Reference substance name:
Butanamide, 2,2'-[(3,3'-dichloro[1,1'-biphenyl]-4,4'-diyl)bis(azo)]bis[3-oxo-, N,N'-bis(phenyl and 2,4-xylyl) derivs.
EC Number:
276-461-9
EC Name:
Butanamide, 2,2'-[(3,3'-dichloro[1,1'-biphenyl]-4,4'-diyl)bis(azo)]bis[3-oxo-, N,N'-bis(phenyl and 2,4-xylyl) derivs.
Cas Number:
72207-62-6
Molecular formula:
C32H26Cl2N6O4 // C34H30Cl2N6O4 // C36H34Cl2N6O4
IUPAC Name:
Butanamide, 2,2'-[(3,3'-dichloro[1,1'-biphenyl]-4,4'-diyl)bis(2,1-diazenediyl)]bis[3-oxo-, N,N'-bis(phenyl and 2,4-xylyl) derivs.

Results and discussion

Particle sizeopen allclose all
Percentile:
D50
Mean:
12.45 µm
Remarks on result:
other: Migrated from fields under 'Mass median diameter' as D50 percentile. No source field for Standard deviation.
Percentile:
D50
Mean:
12.45 µm
St. dev.:
0.19

Any other information on results incl. tables

The values represent averages of three different measurements of the same lot. Individual values: 12.67, 12.33 and 12.35 µm, standard deviation calculated from these values: 0.19 µm.

Applicant's summary and conclusion

Conclusions:
The mass median diameter is 12.45 µm.
Executive summary:
The mass median diameter using Malvern laser diffraction (volumetric distribution) was determined to be 12.45 µm.