Registration Dossier
Registration Dossier
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EC number: 200-662-2 | CAS number: 67-64-1
Long-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
Description of key information
Daphnia magna: 28d-NOEC=2212 mg/L (reproduction)
Key value for chemical safety assessment
Fresh water invertebrates
Fresh water invertebrates
- Dose descriptor:
- NOEC
- Effect concentration:
- 2 212 mg/L
Additional information
Reliable data from studies conducted according to or comparable to OECD Guideline 211 are available. In a study conducted comparable to OECD 211, the 28-day-chronic toxicity of acetone to Daphnia magna was studied under flow -through conditions. The 28-day NOEC based on reproduction was found to be 2212 mg/L (nominal). The 28-day NOEC (MATC) and 28-day LOEC based on mortality of parent individuals was in the range between 1106 and 2212 mg/L (nominal) and 2212 mg/L, respectively. In a further study, the 21-day-chronic toxicity of acetone to Daphnia magna was investigated under semi-static conditions in a study conducted according to OECD Guideline 211. The 21-day NOEC based on reproduction was >= 79 mg/L.
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