Acetic anhydride

Guidance on Safe Use

First-aid measures

Skin contact:  In case of contact, immediately flush skin with plenty of water for at least 15 minutes while removing

contaminated clothing and shoes. Wash clothing before reuse. Clean shoes thoroughly before reuse.

Get medical attention immediately

Eye contact: In case of contact, immediately flush eyes with plenty of water for at least 15 minutes. Get medical

attention immediately.

Inhalation:  If inhaled, remove to fresh air. If not breathing, give artificial respiration. If breathing is difficult, give

oxygen. Get medical attention immediately.

Ingestion:   Do not induce vomiting unless directed to do so by medical personnel. Never give anything by mouth to

an unconscious person. Get medical attention immediately. If swallowed, rinse mouth with water (only if

the person is conscious). If affected person is conscious, give plenty of water to drink.

Fire-fighting measures

Extinguishing media:

Suitable: In case of fire, use water fog, alcohol resistant foam, dry chemical or carbon dioxide extinguisher or spray.

Not suitable: Do not use water jet.

Hazardous decomposition products:

Decomposition products may include the following materials: carbon oxides

Unusual fire/explosion hazards:

Do not allow water to enter container because a violent reaction may occur.

This material is combustible/flammable and is sensitive to fire, heat, and static discharge. Flammable

liquid and vapour. Vapour may cause flash fire. Vapours may accumulate in low or confined areas or

travel a considerable distance to a source of ignition and flash back. Runoff to sewer may create fire or

explosion hazard.

Special fire-fighting procedures:

DO NOT FIGHT FIRE WHEN IT REACHES MATERIAL. Withdraw from fire and let it burn. Promptly isolate the scene by removing all persons from the vicinity of the incident if there is a fire. First move people out of line-of-sight of the scene and away from windows.

Protection of fire-fighters:  Fire-fighters should wear positive pressure self-contained breathing apparatus (SCBA) and full turnout gear. Fire-fighters' protective clothing will only provide limited protection.

Accidental release measures

Personal precautions:

No action shall be taken involving any personal risk or without suitable training. Evacuate surrounding

areas. Keep unnecessary and unprotected personnel from entering. Do not touch or walk through spilt

material. Shut off all ignition sources. No flares, smoking or flames in hazard area. Avoid breathing

vapour or mist. Provide adequate ventilation. Wear appropriate respirator when ventilation is inadequate.

Put on appropriate personal protective equipment.   Respiratory protection  If ventilation is inadequate, use respirator that will protect against organic vapour and dust/mist. Provided an air-filtering/air-purifying respirator is suitable, a combination filter for particles, organic gases and vapours (boiling point >65°C) can be used. Use filter type AP or comparable standard. Respiratory protective equipment must be checked to ensure it fits correctly each time it is worn. Air-filtering respirators, also called air-purifying respirators, will not be adequate under conditions of oxygen deficiency (i.e. low oxygen concentration), and would not be considered suitable where airborne concentrations of

chemicals with a significant hazard are present. In these cases air-supplied breathing apparatus will be

required. If concentration is unknown, a Self-Contained Breathing Apparatus (SCBA) should be used to

avoid inhalation of the product. Hand protection  Wear gloves that cannot be penetrated by chemicals or oil. (Butyl rubber gloves.) The correct choice of protective gloves depends upon the chemicals being handled, the conditions of work and use, and the condition of the gloves (even the best chemically resistant glove will break down after

repeated chemical exposures). Most gloves provide only a short time of protection before they must be

discarded and replaced. Because specific work environments and material handling practices vary, safety

procedures should be developed for each intended application. Gloves should therefore be chosen in

consultation with the supplier/manufacturer and with a full assessment of the working conditions. Eye protection  Do not get in eyes. Wear face shield. Chemical splash goggles. Skin and Body  Do not get on skin or clothing. Wear clothing and footwear that cannot be penetrated by chemicals or oil.

Suitable protective equipment may include:

Hard hat.

Chemical resistant boots.

Chemical resistant apron

Full chemical protective suit with a hood.

Chemical protective suit consisting of a jacket and trousers. The jacket should be buttoned up to the neck,

sleeves sealed at the gloves, and trouser legs worn outside the boots. These precautions are required to

prevent the clothing from accidentally trapping product against the skin.

Environmental precautions:

Avoid dispersal of spilt material and runoff and contact with soil, waterways, drains and sewers. Inform the relevant authorities if the product has caused environmental pollution (sewers, waterways, soil or air).

Large spill:

Stop leak if without risk. Move containers from spill area. Approach the release from upwind. Prevent

entry into sewers, water courses, basements or confined areas. Wash spillages into an effluent treatment

plant or proceed as follows. Contain and collect spillage with non-combustible, absorbent material e.g.

sand, earth, vermiculite or diatomaceous earth and place in container for disposal according to local

regulations . Use spark-proof tools and explosion-proof equipment. Dispose of via a

licensed waste disposal contractor. Contaminated absorbent material may pose the same hazard as the

spilt product. The generation of waste should be avoided or minimised wherever possible. Dispose of via a licensed waste disposal contractor. Disposal  should at all times comply with the requirements of environmental protection and waste disposal legislation and any regional local authority requirements

Small spill:

Stop leak if without risk. Move containers from spill area. Absorb with an inert material and place in an

appropriate waste disposal container. Use spark-proof tools and explosion-proof equipment. Dispose of

via a licensed waste disposal contractor.

Handling and storage

Handling:

Do not ingest. Do not get in eyes, on skin or on clothing. Keep container closed. Use only with adequate

ventilation. Do not breathe vapour or mist. Keep away from heat, sparks and flame. To avoid fire or

explosion, dissipate static electricity during transfer by earthing and bonding containers and equipment

before transferring material. Use explosion-proof electrical (ventilating, lighting and material handling)

equipment. Wash thoroughly after handling.

Storage:

Store in a segregated and approved area. Store in containers made from materials proven to be resistant to the substance under local operating conditions.  Keep container in a cool,

well-ventilated area. Keep container tightly closed and sealed until ready for use. Avoid all possible

sources of ignition (spark or flame). Do not allow water to enter container because a violent reaction may

occur.

Transport information

Shipping

SpecialProvisions

Shipping

Remarks

Marine transport (UN RTDG/IMDG)

Shipping

Remarks

Shipping

Remarks

SpecialProvisions