Registration Dossier
Registration Dossier
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EC number: 237-523-0 | CAS number: 13825-74-6
Short-term toxicity to fish
Administrative data
Link to relevant study record(s)
Description of key information
The conduct of a short-term fish toxicity study with the target substance titanium oxide sulphate itself is being waived, as the substance is highly unstable in water and produces insoluble titanium oxide after rapid hydrolysis. Based on the information available it can be concluded that neither target compound titanium oxide sulphate nor the final hydrolysis transformation products titanium dioxide and sulphuric acid (after neutralisation) exhibit acute toxic effects to fish.
Key value for chemical safety assessment
Additional information
Titanium oxide sulphate rapidly hydrolyses in water, resulting in the formation of titanium dioxide and causing an increase in acidity. Titanium dioxide is very poorly soluble in water. In excess titanium dioxide will be present as insoluble matter. Fish toxicity data for the titanium dioxide in marine and freshwater show the absence of short-term effects in fish at nominal concentrations that are several orders of magnitude higher than the soluble concentration plus additional load of suspended microdisperse matter in excess. Physical effects on fish might occur as a result of fouling, smothering or coating with high loadings of titanium dioxide precipitate, however such effects are not to be attributed to toxic properties of the substance.
It is concluded that final hydrolysis transformation product titanium dioxide does not exhibit acute effects to fish at the level of its water solubility in addition with suspended microdisperse matter in excess, even if ingested.
Concerning the target compound titanium oxysulfate itself, the increase of acidity caused by the rapid hydrolysis reaction to form the other final hydrolysis product sulphuric acid is of no relevance for environmental risk assessment under REACH. Within the environmentally relevant pH range sulfuric acid species are being neutralised and thus rendered harmless to biota.
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