Hexafluoropropene

GHS

General Information

Name:

EU Self Classification

Implementation:

EU

Remarks:

This classification deviates from that found in EU Classification, Labelling and Packaging of Substances and Mixtures (CLP) Regulation (EC) No. 1272/2008 in the following ways: Single exposure target organ toxicity: Data from SIEF support STOT SE Cat 2. Annex VI has no classification for this endpoint. Based on the results of acute inhalation studies, the substance is classified as Specific Target Organ Toxicity – Single Exposure Category 2 (H371, kidney) according to EU Classification, Labelling and Packaging of Substances and Mixtures (CLP) Regulation (EC) No. 1272/2008. Repeat exposure target organ toxicity: Data from SIEF support STOT RE Cat 2. Annex VI has no classification for this endpoint. Based on the results of repeated inhalation studies, the substance is classified as Specific Target Organ Toxicity Repeated Exposure Category 2 (H373, kidney) according to the EU Classification, Labelling and Packaging of Substances and Mixtures (CLP) Regulation (EC) No. 1272/2008. There was no evidence of respiratory irritation during inhalation exposures. Therefore, STOT SE Cat 3 classification may benefit from reconsideration in the future.

Classification

Physical hazards

Explosives

Reason for no classification:

data conclusive but not sufficient for classification

Flammable gases and chemically unstable gases

Reason for no classification:

data conclusive but not sufficient for classification

Aerosols

Reason for no classification:

data conclusive but not sufficient for classification

Reason for no classification:

hazard class not assessed

Oxidising gases

Reason for no classification:

data conclusive but not sufficient for classification

Gases under pressure

Hazard category:

Liquefied gas

Hazard statement:

H280: Contains gas under pressure; may explode if heated.

Flammable liquids

Reason for no classification:

data conclusive but not sufficient for classification

Flammable solids

Reason for no classification:

data conclusive but not sufficient for classification

Self-reactive substances and mixtures

Reason for no classification:

data conclusive but not sufficient for classification

Pyrophoric liquids

Reason for no classification:

data conclusive but not sufficient for classification

Pyrophoric solids

Reason for no classification:

data conclusive but not sufficient for classification

Self-heating substances and mixtures

Reason for no classification:

data conclusive but not sufficient for classification

Substances and mixtures which in contact with water emit flammable gases

Reason for no classification:

data conclusive but not sufficient for classification

Oxidising liquids

Reason for no classification:

data conclusive but not sufficient for classification

Oxidising solids

Reason for no classification:

data conclusive but not sufficient for classification

Organic peroxides

Reason for no classification:

data conclusive but not sufficient for classification

Corrosive to metals

Reason for no classification:

data conclusive but not sufficient for classification

Desensitized explosives

Reason for no classification:

data lacking

Health hazards

Acute toxicity - oral

Reason for no classification:

data conclusive but not sufficient for classification

Acute toxicity - dermal

Reason for no classification:

data conclusive but not sufficient for classification

Acute toxicity - inhalation

Hazard category:

Acute Tox. 4

Hazard statement:

H332: Harmful if inhaled.

Skin corrosion / irritation

Reason for no classification:

data conclusive but not sufficient for classification

Serious eye damage / eye irritation

Reason for no classification:

data conclusive but not sufficient for classification

Respiratory sensitisation

Reason for no classification:

data conclusive but not sufficient for classification

Skin sensitisation

Reason for no classification:

data conclusive but not sufficient for classification

Aspiration hazard

Reason for no classification:

data lacking

Reproductive toxicity

Reason for no classification:

data conclusive but not sufficient for classification

Effects on or via lactation

Reason for no classification:

data lacking

Germ cell mutagenicity

Reason for no classification:

data conclusive but not sufficient for classification

Carcinogenicity

Hazard category:

Carc. 2

Hazard statement:

H351: Suspected of causing cancer <state route of exposure if it is conclusively proven that no other routs of exposure cause the hazard>.

1. Specific target organ toxicity - single (STOT-SE)

Hazard category:

STOT Single Exp. 3

Hazard statement:

H335: May cause respiratory irritation.

Affected organs:

other: Respiratory

Route of exposure:

inhalation

2. Specific target organ toxicity - single (STOT-SE)

Hazard category:

STOT Single Exp. 2

Hazard statement:

H371: May cause damage to organs <or state all organs affected, if known> <state route of exposure if it is conclusively proven that no other routes of exposure cause the hazard>.

Affected organs:

other: Kidneys

Route of exposure:

inhalation

1. Specific target organ toxicity - repeated (STOT-RE)

Hazard category:

STOT Rep. Exp. 2

Hazard statement:

H373: May cause damage to organs <or state all organs affected, if known> through prolonged or repeated exposure <state route of exposure if it is conclusively proven that no other routes of exposure cause the hazard>.

Affected organs:

other: Kidneys

Route of exposure:

inhalation

Environmental hazards

Hazardous to the aquatic environment (acute / short-term)

Reason for no classification:

data conclusive but not sufficient for classification

Hazardous to the aquatic environment (long-term)

Reason for no classification:

data conclusive but not sufficient for classification

Hazardous to the ozone layer

Reason for no classification:

data conclusive but not sufficient for classification

Labelling

Signal word:

Warning

Hazard pictogram

GHS08: health hazard

GHS04: gas cylinder

GHS07: exclamation mark

Hazard statements

H351: Suspected of causing cancer <state route of exposure if it is conclusively proven that no other routs of exposure cause the hazard>.

H373: May cause damage to organs <or state all organs affected, if known> through prolonged or repeated exposure <state route of exposure if it is conclusively proven that no other routes of exposure cause the hazard>.

H371: May cause damage to organs <or state all organs affected, if known> <state route of exposure if it is conclusively proven that no other routes of exposure cause the hazard>.

H332: Harmful if inhaled.

H280: Contains gas under pressure; may explode if heated.

H335: May cause respiratory irritation.

Precautionary statements

P201: Obtain special instructions before use.

P260: Do not breathe dust/fume/gas/mist/vapours/spray.

P280: Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/...

P304+P340: IF INHALED: Remove person to fresh air and keep comfortable for breathing.

P403+P233: Store in a well-ventilated place. Keep container tightly closed.

P308+P311: IF exposed or concerned: Call a POISON CENTER/doctor/…

Notes

Note U (Table 3)