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EC number: 265-062-5
CAS number: 64741-60-2
A complex combination of hydrocarbons produced by the distillation of products from a catalytic cracking process. It consists of hydrocarbons having carbon numbers predominantly in the range of C11 through C30 and boiling in the range of approximately 205°C to 450°C (401°F to 842°F). It contains a relatively large proportion of tricyclic aromatic hydrocarbons.
In an 90 -day dermal toxicity study, Light
Catalytically Cracked Distillate was applied to the shaved skin of 10
males and 10 females per dose at dose levels of 8, 25, 125, and 500 and
1,250 mg/kg/day, for 5 days/week during a 90 -day period.
Dermal treatment with Light Catalytically
Cracked Distillate at doses of 125, 500 and/or 1,250 mg/kg/day resulted
in reductions in body weight,thymus weight and an increase in liver
weight. Severe erythema and edema was also reported. Histopathologic
evaluation was limited to control animals and those dosed at 500
mg/kg/day. A NOEL was calculated as 25 mg/kg/day for males and 125
mg/kg/day for females.
This study received a Klimisch score of 2
and is classified as reliable with restrictions because it is an
acceptable and well documented study report.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
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