Registration Dossier
Registration Dossier
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EC number: 500-111-9 | CAS number: 51728-26-8 1 - 8.5 moles ethoxylated
Endpoint summary
Administrative data
Description of key information
The test subtance is not acutely toxic for the oral and dermal route. In both studies, the LD50 is >2000 mg/kg bw.
Key value for chemical safety assessment
Acute toxicity: via oral route
Endpoint conclusion
- Endpoint conclusion:
- no adverse effect observed
- Dose descriptor:
- LD50
- Value:
- 2 000 mg/kg bw
Acute toxicity: via inhalation route
Endpoint conclusion
- Endpoint conclusion:
- no study available
Acute toxicity: via dermal route
Endpoint conclusion
- Endpoint conclusion:
- no adverse effect observed
- Dose descriptor:
- LD50
- Value:
- 2 000 mg/kg bw
Additional information
Based on the available information, the acute toxcity of the test substance is low for the oral and dermal route of administration. In both studies, the LD50 is >2000 mg/kg bw. There is no study available for the inhalation route. Even though there is no information on acute toxicity is humans, there is no resaon to believe that the low acute toxicty observed in experimental animals would not be relevant for human health.
Justification for selection of acute toxicity – oral endpoint
Study conducted according to OECD guideline 423 and under GLP.
Justification for selection of acute toxicity – dermal endpoint
Study conducted according to OECD guideline and under GLP.
Justification for classification or non-classification
Based on the available data, the substance does not need to be classified for acute toxicity, according to the Regulation EC 1272/2008 and the Directive 67/548/EEC.
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