Registration Dossier
Registration Dossier
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EC number: 201-116-6 | CAS number: 78-42-2
Solubility in organic solvents / fat solubility
Administrative data
Link to relevant study record(s)
- Endpoint:
- solubility in organic solvents / fat solubility
- Adequacy of study:
- key study
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- other: The study is well conducted and reported to GLP standards. The method used is appropriate for the levels of solubility seen within these organic solvents in the prelimenary and final tests as per OECD guideline 105.
- Qualifier:
- according to guideline
- Guideline:
- other: OECD test 105 with modification
- GLP compliance:
- yes (incl. QA statement)
- Medium:
- acetone
- Solubility:
- 698.8 g/L
- Temp.:
- 20 °C
- Medium:
- methanol
- Solubility:
- 699.2 g/L
- Temp.:
- 20 °C
- Conclusions:
- The test substance is soluble in acetone and methonal at a level of 698.8 g/L and 699.20 g/L. The substance is moderately soluble in both methanol and acetone.
- Executive summary:
The solubility of tris(2 -ethylhexyl)phosphate was determined using OECD 105 guidelines, using the shake flask method.
The solubility of tris(2 -ethylhexyl)phosphate was determined to be 698.80 g/L and 699.20 g/L in acetone and methanol respectively.
In these organic substances the test substance is moderately soluble.
Reference
Description of key information
Solubility in organic solvent: Acetone = 698.8 g/L, Methanol = 699.2 g/L; OECD 105; Zen (2013)
Key value for chemical safety assessment
Additional information
Zen (2013) conducted a solubility study in two organic solvents using OECD 105 methodology. Solubility in acetone and methanol was 698.8 g/L and 699.2 g/L respectively.
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