Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 202-707-1 | CAS number: 98-85-1
Basic toxicokinetics
Administrative data
- Endpoint:
- basic toxicokinetics
- Type of information:
- not specified
- Adequacy of study:
- supporting study
- Reliability:
- 4 (not assignable)
- Rationale for reliability incl. deficiencies:
- other: Data from secondary literature source.
Data source
Reference
- Reference Type:
- secondary source
- Title:
- Hazardous Substances Data Bank (HSDB), Alpha-Methylbenzyl Alcohol
- Author:
- United States National Library of Medicine
- Year:
- 2 010
Materials and methods
- Objective of study:
- metabolism
- Principles of method if other than guideline:
- Metabolites of the substance was identified.
- GLP compliance:
- not specified
Test material
- Reference substance name:
- 1-phenylethanol
- EC Number:
- 202-707-1
- EC Name:
- 1-phenylethanol
- Cas Number:
- 98-85-1
- Molecular formula:
- C8H10O
- IUPAC Name:
- 1-phenylethan-1-ol
- Details on test material:
- - Name of test material (as cited in study report): 1-Phenylethanol
Constituent 1
- Radiolabelling:
- not specified
Test animals
- Species:
- rat
- Strain:
- not specified
- Sex:
- not specified
Administration / exposure
- Vehicle:
- not specified
- Duration and frequency of treatment / exposure:
- No data
Doses / concentrations
- Remarks:
- Doses / Concentrations:
No data
- No. of animals per sex per dose / concentration:
- No data
- Control animals:
- not specified
Results and discussion
- Preliminary studies:
- No data
Metabolite characterisation studies
- Metabolites identified:
- yes
- Details on metabolites:
- Acetophenones
Applicant's summary and conclusion
- Conclusions:
- Interpretation of results (migrated information): bioaccumulation potential cannot be judged based on study results
Dehydrogenase present in rat cytosol and microsomes converts 1-phenylethanol into acetophenones. - Executive summary:
Dehydrogenase present in rat cytosol and microsomes converts 1-phenylethanol into acetophenones. Data from secondary literature source therefore a reliability of 4 is assigned.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
