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EC number: 242-734-6 | CAS number: 18996-35-5
Short-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
Description of key information
(24 h) EC50 1705 mg/L D. magna
Key value for chemical safety assessment
Fresh water invertebrates
Fresh water invertebrates
- Effect concentration:
- 1 705 mg/L
Additional information
No data on toxicity of sodium dihydrogen citrate 18996 -35 -5 to aquatic invertebrates are available. A 24 h aquatic invertebrate study is, however, available for the parent acid of sodium dihydrogen citrate, citric acid 77-92 -9 with D. magna in a neutralised solution. It is considered appropriate to read across the aquatic invertebrate results to sodium dihydrogen citrate 18996 -35 -5 because under conditions relevant to ecotoxicity assessment, the sodium dihydrogen salt of citric acid is expected to be fully dissociated. Sodium dihydrogen is not expected to contribute to the toxicity of the substance, being a ubiquitous element.
The study determines an LC50 value based on mortality of the test organism, by today's standards it is thought by the reviewer to be more accurate to refer to an EC50 value based on immobility, due to the difficulties is determining mortality of daphnids by visual inspection. Therefore a 24 h EC50 value of 1535 mg/L was determined for the effects of citric acid 77 -92 -9 on D. magna.
The resulting EC50 for citric acid is 1535 mg/L, which is equivalent to 1535 * 1.11 = 1705 mg/L of sodium dihydrogen citrate.
(using MW(sodium dihydrogen citrate)/MW(citric acid) = 214.11/192.9 = 1.11)Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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