Registration Dossier
Registration Dossier
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EC number: 200-540-9 | CAS number: 62-54-4
Acute Toxicity: other routes
Administrative data
- Endpoint:
- acute toxicity: other routes
- Type of information:
- experimental study
- Adequacy of study:
- supporting study
- Study period:
- 1961
- Reliability:
- 3 (not reliable)
- Rationale for reliability incl. deficiencies:
- other: No specific test guideline was reported; however, a scientifically defensible approach was used to conduct the study.
Data source
Reference
- Reference Type:
- publication
- Title:
- Unnamed
- Year:
- 1 961
- Report date:
- 1961
Materials and methods
Test guideline
- Qualifier:
- no guideline followed
- Principles of method if other than guideline:
- The LD50 was determinated by intraperitoneal application of calcium acetate to inbred female mice (AGNES-BLUHM strain).
- GLP compliance:
- no
- Limit test:
- no
Test material
- Reference substance name:
- Calcium di(acetate)
- EC Number:
- 200-540-9
- EC Name:
- Calcium di(acetate)
- Cas Number:
- 62-54-4
- Molecular formula:
- C2H4O2.1/2Ca
- IUPAC Name:
- calcium diacetate
- Details on test material:
- - Name of test material (as cited in study report): Calcium acetate
- Substance type: discrete
- Physical state: solid
Constituent 1
Test animals
- Species:
- mouse
- Strain:
- other: Agnes-Bluhm
- Sex:
- female
Administration / exposure
- Route of administration:
- intraperitoneal
- Vehicle:
- not specified
- Doses:
- No data
- No. of animals per sex per dose:
- 83 female mice
- Control animals:
- not specified
Results and discussion
Effect levels
- Sex:
- female
- Dose descriptor:
- LD50
- Effect level:
- 74.5 mg/kg bw
- Based on:
- test mat.
Any other information on results incl. tables
The result of the assay performed in 83 mice was: LD50 = 74.5 mg/kg bw.
Applicant's summary and conclusion
- Conclusions:
- The (48h) LD50 was 74.5 mg/kg bw.
- Executive summary:
The result of calcium acetate LD50 assay was 74.5 mg/kg bw. The test was performed in 83 inbred female mice (Agnes-Bluhm strain) and the observation time was 48 hours.
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