Registration Dossier
Registration Dossier
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EC number: 217-793-6 | CAS number: 1955-46-0
Endpoint summary
Administrative data
Description of key information
The substance do not show any repeated dose toxicity.
Key value for chemical safety assessment
Repeated dose toxicity: via oral route - systemic effects
Endpoint conclusion
- Endpoint conclusion:
- no adverse effect observed
- Dose descriptor:
- LOAEL
- 735.11 mg/kg bw/day
- Study duration:
- subchronic
- Species:
- rat
- Quality of whole database:
- predicted data
Additional information
Repeated dose - oral category:
Repeated dose LOEL effect on rat for methyl 5-nitrohydrogen.isophthalate is found to 735.11 mg/kg/day
Repeated dose - inhalation category:
Repeated dose LOEL effect on rat for methyl 5-nitrohydrogen.isophthalate is found to 52.64 mg/kg/day
Repeated dose - dermal category:
According to annex IX of REACH regulation, Short-term repeated dose toxicity study (28 days) does not need to be conducted if one species, male and female, most appropriate route of administration, having regard to the likely route of human exposure, unless already provided as part of Annex VIII requirements. since acute toxicity dermal route has been provided as part of annex VIII requirements.
Justification for classification or non-classification
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
