Registration Dossier
Registration Dossier
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EC number: 205-465-5 | CAS number: 141-17-3
Endpoint summary
Administrative data
Description of key information
Additional information
Based on an experimental study, Bis(2-(2-butoxyethoxy)ethyl) adipate (CAS 141-17-3) is readily biodegradable according to OECD criteria (82% biodegradation after 28 d, OECD 301B). Therefore, the substance will not be persistent in the environment. Abitoc degradation via hydrolysis is not considered to be a relevant degradation pathway in the environment. This assumption is supported by QSAR calculations estimating a half-life (DT50) of 294 days at pH 7 for the substance (HYDROWIN v2.00). Evaporation into air and subsequent transport through the atmosphere to other environmental compartments is not expected due to the low vapour pressure (< 0.0001 Pa at 20 °C).
Bis(2-(2-butoxyethoxy)ethyl) adipate is soluble in water (570 mg/L at 20 °C) and has low adsorption potential, based on calculated estimate (log Koc 2.2, KOCWIN v2.00). Consequently, the main target compartment in the environment is expected to be the aquatic compartment. However, due to the ready biodegradability, the substance is expected to be rapidly removed from the water phase.
Based on the rapid environmental biodegradation and metabolism via enzymatic hydrolysis, relevant uptake and bioaccumulation in aquatic organisms is not expected. Enzymatic breakdown will initially lead to the free fatty acid and the free alcohol. From literature it is well known, that these products of hydrolysis will be metabolised and effectively excreted in fish (for further information see Chapter 5.3 of the technical dossier). This is supported by a low BCF value of 6.33 L/kg ww (BCFBAF v3.01; Arnot-Gobas, including biotransformation, upper trophic).
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