Registration Dossier
Registration Dossier
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EC number: 203-960-0 | CAS number: 112-33-4
Toxicity to microorganisms
Administrative data
Link to relevant study record(s)
Description of key information
The inhibition of the degradation activity of activated sludge is not anticipated when introduced in appropriately low concentrations.
Key value for chemical safety assessment
- EC50 for microorganisms:
- 450 mg/L
- EC10 or NOEC for microorganisms:
- 280 mg/L
Additional information
The inhibitory effect of 2[-2 -(3 -aminopropoxy)ethoxy]ethanol (CAS 112 -33 -4) was studied in a growth inhibition test under GLP and according to German Industrial Standard DIN 38412, part 8 on Pseudomonas putida. The 16 -h EC10 was determined to be 280 mg/L (nominal; not neutralised test solutions). The neutralised test sample of the highest test concentration (10000 mg/L, pH 7.0) caused an inhibition of 50% while the not neutralised test sample of the same concentration (10000 mg/L, pH 11) caused a complete inhibition on growth. The neutralised and not neutralised test solution (pH 7.6 and 9.8) caused no inhibition on growth compared to the control (BASF AG, 1992; report no. 91/1782/70/2).
It can be concluded that inhibition of the degradation activity of activated sludge is not anticipated when introduced in appropriately low concentrations.
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